C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HtrA serine peptidase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000068329 Htra2 10090 - 6:83051266-83055273 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000089645 Htra2-001 83051266-83054571 protein_coding
  ENSMUST00000113962 Htra2-002 83051266-83054442 protein_coding
  ENSMUST00000113963 Htra2-004 83051266-83054571 protein_coding
  ENSMUST00000122955 Htra2-003 83051280-83054571 nonsense_mediated_decay
  ENSMUST00000132099 Htra2-008 83051387-83053686 nonsense_mediated_decay
  ENSMUST00000134606 Htra2-007 83051477-83053837 protein_coding
  ENSMUST00000144058 Htra2-009 83051486-83053837 retained_intron
  ENSMUST00000150217 Htra2-005 83051749-83054037 protein_coding
  ENSMUST00000154829 Htra2-006 83051284-83055273 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainHeartLiverMuscleOvaryPlacentaENSMUST00000089645ENSMUST00000154829
Transcript ID Adipose Bladder Brain Heart Liver Muscle Ovary Placenta
ENSMUST00000089645 18.342±3.57 14.971±3.34 16.208±1.24 11.025±2.32 41.994±18.37 8.019±0.73 16.240±0.00 14.431±1.65
ENSMUST00000154829 N/A N/A N/A N/A 15.836±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000785 IEA chromatin
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0005758 ISO mitochondrial intermembrane space
GO:0005829 IEA cytosol
GO:0005856 IEA cytoskeleton
GO:0006508 IEA proteolysis
GO:0006672 IEA ceramide metabolic process
GO:0007005 IMP mitochondrion organization
GO:0007628 IMP adult walking behavior
GO:0008233 IEA peptidase activity
GO:0008236 IEA serine-type peptidase activity
GO:0008344 IMP adult locomotory behavior
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009635 IEA response to herbicide
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0010942 IEA positive regulation of cell death
GO:0016020 IEA membrane
GO:0019742 IEA pentacyclic triterpenoid metabolic process
GO:0030900 IMP forebrain development
GO:0034605 IEA cellular response to heat
GO:0035458 IEA cellular response to interferon-beta
GO:0035631 IDA CD40 receptor complex
GO:0040014 IMP regulation of multicellular organism growth
GO:0043065 IMP positive regulation of apoptotic process
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044257 IEA cellular protein catabolic process
GO:0048666 IMP neuron development
GO:0060548 IEA negative regulation of cell death
GO:0071300 IEA cellular response to retinoic acid
GO:0071363 IEA cellular response to growth factor stimulus
GO:0097193 IMP intrinsic apoptotic signaling pathway
GO:2001241 IEA positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001269 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068667 HTRA2 (1 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000068800 HTRA2 (2 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000068819 HTRA2 (3 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000069909 HTRA2 (4 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000070138 HTRA2 (5 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000076713 HTRA2 (6 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000088743 HTRA2 (7 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000089070 HTRA2 (8 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000090177 HTRA2 (9 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000092061 HTRA2 (10 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000092094 HTRA2 (11 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000092133 HTRA2 (12 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000092202 HTRA2 (13 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000092380 HTRA2 (14 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000092625 HTRA2 (15 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000092951 HTRA2 (16 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000093005 HTRA2 (17 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000093522 HTRA2 (18 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000093729 HTRA2 (19 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000093963 HTRA2 (20 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000094236 HTRA2 (21 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000094403 HTRA2 (22 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000094713 HTRA2 (23 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000094741 HTRA2 (24 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000094749 HTRA2 (25 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000094878 HTRA2 (26 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000094995 HTRA2 (27 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000095314 HTRA2 (28 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000095444 HTRA2 (29 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000095545 HTRA2 (30 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSDARG00000095687 HTRA2 (31 of 31) HtrA serine peptidase 2 protein_coding Danio_rerio
ENSG00000115317 HTRA2 HtrA serine peptidase 2 protein_coding Homo_sapiens

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