C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: HtrA serine peptidase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000089645 Htra2-001 ENSMUSG00000068329 10090 - 6:83051266-83054571 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainHeartLiverMuscleOvaryPlacentaENSMUST00000089645
Transcript ID Adipose Bladder Brain Heart Liver Muscle Ovary Placenta
ENSMUST00000089645 18.342±3.57 14.971±3.34 16.208±1.24 11.025±2.32 41.994±18.37 8.019±0.73 16.240±0.00 14.431±1.65

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000785 IEA chromatin
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0005758 ISO mitochondrial intermembrane space
GO:0005829 IEA cytosol
GO:0005856 IEA cytoskeleton
GO:0006508 IEA proteolysis
GO:0006672 IEA ceramide metabolic process
GO:0007005 IMP mitochondrion organization
GO:0007628 IMP adult walking behavior
GO:0008233 IEA peptidase activity
GO:0008236 IEA serine-type peptidase activity
GO:0008344 IMP adult locomotory behavior
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009635 IEA response to herbicide
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0010942 IEA positive regulation of cell death
GO:0016020 IEA membrane
GO:0019742 IEA pentacyclic triterpenoid metabolic process
GO:0030900 IMP forebrain development
GO:0034605 IEA cellular response to heat
GO:0035458 IEA cellular response to interferon-beta
GO:0035631 IDA CD40 receptor complex
GO:0040014 IMP regulation of multicellular organism growth
GO:0043065 IMP positive regulation of apoptotic process
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044257 IEA cellular protein catabolic process
GO:0048666 IMP neuron development
GO:0060548 IEA negative regulation of cell death
GO:0071300 IEA cellular response to retinoic acid
GO:0071363 IEA cellular response to growth factor stimulus
GO:0097193 IMP intrinsic apoptotic signaling pathway
GO:2001241 IEA positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001269 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000258080 HTRA2-001 protein_coding Homo_sapiens 0 1663
ENST00000264094 LOXL3-001 protein_coding Homo_sapiens 0 322
ENST00000352222 HTRA2-002 protein_coding Homo_sapiens 0 625
ENST00000393937 LOXL3-002 protein_coding Homo_sapiens 0.00000000003 75
ENST00000409249 LOXL3-005 protein_coding Homo_sapiens 0 322
ENST00000437202 HTRA2-005 protein_coding Homo_sapiens 0 880
ENST00000462909 HTRA2-003 processed_transcript Homo_sapiens 0 1288
ENST00000465521 HTRA2-010 retained_intron Homo_sapiens 0 614
ENST00000467961 HTRA2-004 processed_transcript Homo_sapiens 0 1295
ENST00000470907 LOXL3-006 retained_intron Homo_sapiens 0 322
ENST00000482205 HTRA2-009 retained_intron Homo_sapiens 0 486
ENST00000482331 HTRA2-007 retained_intron Homo_sapiens 0 538
ENST00000484352 HTRA2-006 retained_intron Homo_sapiens 0 773
ENST00000484881 HTRA2-008 processed_transcript Homo_sapiens 0 538

Loading