C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sodium channel, voltage-gated, type II, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000070304 Scn2b 10090 + 9:45117876-45130070 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000093855 Scn2b-201 45117881-45130068 protein_coding
  ENSMUST00000170998 Scn2b-202 45117876-45130070 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000093855ENSMUST00000170998
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000093855 0.315±0.24 0.912±0.33 0.059±0.00 N/A 0.330±0.00 0.375±0.10 0.072±0.05 0.202±0.09 0.035±0.02 0.075±0.02 0.147±0.07 0.392±0.26 0.018±0.00 0.090±0.04
ENSMUST00000170998 0.780±0.68 0.939±0.31 0.112±0.01 13.715±16.40 0.447±0.18 0.475±0.20 0.075±0.03 0.160±0.08 0.099±0.04 0.186±0.08 0.192±0.11 0.774±0.33 0.102±0.06 0.241±0.20

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081E CIL_00081E_0002 VISTA 9:44577224-45180192
CIL_0003MC CIL_0003MC_0002 CGP 9:45117876-45154152

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005248 IEA voltage-gated sodium channel activity
GO:0007399 IEA nervous system development
GO:0017080 IEA sodium channel regulator activity
GO:0035725 IEA sodium ion transmembrane transport
GO:0046684 IEA response to pyrethroid
GO:0060048 IEA cardiac muscle contraction
GO:0060371 IEA regulation of atrial cardiac muscle cell membrane depolarization
GO:0086002 IEA cardiac muscle cell action potential involved in contraction
GO:0086006 IEA voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0086012 IEA membrane depolarization during cardiac muscle cell action potential
GO:0086091 IEA regulation of heart rate by cardiac conduction
GO:2000649 IEA regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041176 scn2b sodium channel, voltage-gated, type II, beta protein_coding Danio_rerio
ENSG00000149575 SCN2B sodium channel, voltage-gated, type II, beta subunit protein_coding Homo_sapiens

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