C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin D1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000070348 Ccnd1 10090 - 7:144929931-144939869 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000093962 Ccnd1-001 144929931-144939869 protein_coding
  ENSMUST00000135985 Ccnd1-002 144937295-144938197 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000093962
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000093962 26.693±9.70 93.122±2.94 44.934±3.37 14.767±7.72 31.387±15.35 49.600±1.28 12.495±3.16 79.215±4.38 22.897±10.24 82.638±18.27 1.636±0.28 34.934±16.51 5.699±2.65 3.519±1.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TF CIL_0007TF_0002 VISTA 7:144693485-145297342
CIL_0007SN CIL_0007SN_0002 VISTA 7:144817158-145418950

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 ISS G1/S transition of mitotic cell cycle
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000307 IPI cyclin-dependent protein kinase holoenzyme complex
GO:0000320 IDA re-entry into mitotic cell cycle
GO:0001889 IEA liver development
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0003714 ISS transcription corepressor activity
GO:0004672 IDA protein kinase activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005923 IDA tight junction
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0007595 IMP lactation
GO:0008134 IEA transcription factor binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0010033 IEA response to organic substance
GO:0010039 IEA response to iron ion
GO:0010165 IEA response to X-ray
GO:0010243 IEA response to organonitrogen compound
GO:0010971 ISS positive regulation of G2/M transition of mitotic cell cycle
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0016055 IDA Wnt signaling pathway
GO:0016301 IDA kinase activity
GO:0016538 IDA cyclin-dependent protein serine/threonine kinase regulator activity
GO:0017053 ISS transcriptional repressor complex
GO:0019899 IEA enzyme binding
GO:0019901 IPI protein kinase binding
GO:0030178 IMP negative regulation of Wnt signaling pathway
GO:0030857 IGI negative regulation of epithelial cell differentiation
GO:0030968 IDA endoplasmic reticulum unfolded protein response
GO:0031100 IEA organ regeneration
GO:0031571 ISS mitotic G1 DNA damage checkpoint
GO:0032026 IEA response to magnesium ion
GO:0032403 IEA protein complex binding
GO:0033197 IEA response to vitamin E
GO:0033327 IEA Leydig cell differentiation
GO:0033598 IGI mammary gland epithelial cell proliferation
GO:0033601 IGI positive regulation of mammary gland epithelial cell proliferation
GO:0042493 IEA response to drug
GO:0042826 IEA histone deacetylase binding
GO:0043627 IEA response to estrogen
GO:0045444 IDA fat cell differentiation
GO:0045471 IEA response to ethanol
GO:0045737 ISS positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0048545 IEA response to steroid hormone
GO:0051301 IEA cell division
GO:0051384 IEA response to glucocorticoid
GO:0051412 IEA response to corticosterone
GO:0051592 IEA response to calcium ion
GO:0051726 IDA regulation of cell cycle
GO:0060070 IMP canonical Wnt signaling pathway
GO:0060749 IMP mammary gland alveolus development
GO:0070064 IEA proline-rich region binding
GO:0070141 ISS response to UV-A
GO:0071157 ISS negative regulation of cell cycle arrest
GO:0071310 IDA cellular response to organic substance
GO:2000045 IGI regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035750 ccnd1 cyclin D1 protein_coding Danio_rerio
ENSG00000110092 CCND1 cyclin D1 protein_coding Homo_sapiens

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