C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neutrophil cytosolic factor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000071715 Ncf4 10090 + 15:78244801-78262580 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000096357 Ncf4-001 78244801-78262580 protein_coding
  ENSMUST00000126028 Ncf4-004 78253246-78260769 processed_transcript
  ENSMUST00000133618 Ncf4-002 78244844-78260994 protein_coding
  ENSMUST00000146147 Ncf4-005 78255452-78260802 retained_intron
  ENSMUST00000147303 Ncf4-003 78253032-78256030 retained_intron
  ENSMUST00000148646 Ncf4-006 78260878-78262575 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000096357ENSMUST00000133618ENSMUST00000146147ENSMUST00000147303ENSMUST00000148646
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000096357 1.967±0.35 0.606±0.30 5.577±1.26 0.192±0.04 7.522±1.92 2.042±0.62 0.677±0.23 0.982±0.47 4.340±5.12 4.323±0.65 0.396±0.54 1.395±0.76 0.570±0.26 0.186±0.01
ENSMUST00000133618 N/A 0.850±0.16 N/A 0.109±0.00 N/A 1.757±0.00 0.353±0.00 0.465±0.20 N/A 2.171±0.00 0.077±0.02 0.402±0.21 0.151±0.00 0.357±0.20
ENSMUST00000146147 N/A N/A N/A N/A N/A N/A N/A N/A 0.930±0.00 N/A N/A 1.758±0.00 0.645±0.38 N/A
ENSMUST00000147303 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.107±0.00 0.111±0.00 N/A
ENSMUST00000148646 N/A 0.600±0.00 N/A 0.169±0.00 N/A N/A 0.406±0.00 0.631±0.05 20.735±8.71 N/A 0.456±0.53 0.803±0.22 3.673±3.28 0.102±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006F3 CIL_0006F3_0003 CGP 15:78191114-78262580
CIL_0003GY CIL_0003GY_0002 CGP 15:78244801-78305603

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 ISS cytosol
GO:0010008 ISS endosome membrane
GO:0016020 ISS membrane
GO:0016176 ISS superoxide-generating NADPH oxidase activator activity
GO:0032266 ISS phosphatidylinositol-3-phosphate binding
GO:0035091 IEA phosphatidylinositol binding
GO:0043020 IEA NADPH oxidase complex
GO:0043085 IEA positive regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040812 ncf4 neutrophil cytosolic factor 4 protein_coding Danio_rerio
ENSG00000100365 NCF4 neutrophil cytosolic factor 4, 40kDa protein_coding Homo_sapiens

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