C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neutrophil cytosolic factor 4, 40kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100365 NCF4 9606 + 22:36860988-36878015 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000248899 NCF4-001 36860988-36878015 protein_coding
  ENST00000397147 NCF4-002 36860988-36878015 protein_coding
  ENST00000415063 NCF4-003 36872137-36877764 protein_coding
  ENST00000447071 NCF4-004 36860988-36875832 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000248899ENST00000397147ENST00000415063ENST00000447071
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000248899 5.120±0.00 12.641±0.00 0.236±0.00 0.738±0.35 N/A 1.379±0.11 1.346±1.27 1.612±0.99 2.527±0.10 6.780±3.34 N/A 2.835±1.11 24.831±9.76 0.982±0.38
ENST00000397147 N/A 4.243±0.00 N/A N/A 1.236±0.13 N/A 0.334±0.00 N/A N/A 4.378±0.00 0.204±0.15 1.109±0.00 N/A 0.493±0.00
ENST00000415063 N/A N/A N/A N/A 0.678±0.00 N/A N/A N/A N/A N/A N/A 2.707±0.00 17.743±0.00 0.653±0.00
ENST00000447071 N/A N/A 0.260±0.00 N/A N/A 1.452±0.00 0.151±0.00 N/A N/A N/A 0.256±0.00 N/A N/A 0.449±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006F3 CIL_0006F3_0002 CGP 22:36800684-36878015
CIL_0003GY CIL_0003GY_0001 CGP 22:36860988-36940449

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006955 TAS immune response
GO:0010008 IDA endosome membrane
GO:0016020 IDA membrane
GO:0016176 IMP superoxide-generating NADPH oxidase activator activity
GO:0032010 TAS phagolysosome
GO:0032266 IDA phosphatidylinositol-3-phosphate binding
GO:0035091 IEA phosphatidylinositol binding
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0043020 IDA NADPH oxidase complex
GO:0043085 IMP positive regulation of catalytic activity
GO:0046983 TAS protein dimerization activity
GO:0051701 TAS interaction with host
GO:0055114 TAS oxidation-reduction process
GO:0090382 TAS phagosome maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040812 ncf4 neutrophil cytosolic factor 4 protein_coding Danio_rerio
ENSMUSG00000071715 Ncf4 neutrophil cytosolic factor 4 protein_coding Mus_musculus

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