C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peptidoglycan recognition protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000079563 Pglyrp2 10090 - 17:32413100-32424167 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000114455 Pglyrp2-201 32413361-32424167 protein_coding
  ENSMUST00000170392 Pglyrp2-202 32413100-32420975 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000114455ENSMUST00000170392
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000114455 0.307±0.11 N/A 0.102±0.06 0.020±0.00 7.754±4.15 0.509±0.29 0.063±0.01 0.547±0.28 1.922±1.06 0.813±0.28 0.276±0.24 0.315±0.13 0.053±0.02 0.477±0.24
ENSMUST00000170392 0.048±0.00 0.311±0.06 0.032±0.00 N/A 4.857±1.93 0.627±0.26 N/A 0.291±0.15 45.599±39.13 0.283±0.12 N/A 0.222±0.18 0.011±0.00 0.287±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00019W CIL_00019W_0002 CGP 17:32390659-32424167
CIL_0001MH CIL_0001MH_0002 CGP 17:32413100-32492479

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002221 IEA pattern recognition receptor signaling pathway
GO:0008270 IEA zinc ion binding
GO:0008745 IEA N-acetylmuramoyl-L-alanine amidase activity
GO:0009253 IEA peptidoglycan catabolic process
GO:0016019 ISS peptidoglycan receptor activity
GO:0016020 IEA membrane
GO:0016045 ISS detection of bacterium
GO:0032689 IMP negative regulation of interferon-gamma production
GO:0032827 IMP negative regulation of natural killer cell differentiation involved in immune response
GO:0042834 ISS peptidoglycan binding
GO:0044117 IMP growth of symbiont in host
GO:0050727 IMP regulation of inflammatory response
GO:0050830 ISS defense response to Gram-positive bacterium
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015626 pglyrp6 peptidoglycan recognition protein 6 protein_coding Danio_rerio
ENSDARG00000062998 pglyrp2 peptidoglycan recognition protein 2 protein_coding Danio_rerio
ENSG00000161031 PGLYRP2 peptidoglycan recognition protein 2 protein_coding Homo_sapiens

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