C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glucokinase (hexokinase 4)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000616242 GCK-201 ENSG00000106633 9606 - 7:44144271-44158114 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastHeartLiverENST00000616242
Transcript ID Brain Breast Heart Liver
ENST00000616242 0.303±0.00 0.112±0.00 0.044±0.00 0.406±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006I9 CIL_0006I9_0002 CGP 7:44138864-44198170
CIL_0000J5 CIL_0000J5_0001 CGP 7:44144271-44214294

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001678 IBA cellular glucose homeostasis
GO:0004340 IDA glucokinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005536 IDA glucose binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005975 TAS:IEA carbohydrate metabolic process
GO:0006110 NAS regulation of glycolytic process
GO:0008645 TAS hexose transport
GO:0010827 TAS regulation of glucose transport
GO:0015758 TAS glucose transport
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0031018 TAS endocrine pancreas development
GO:0032024 IMP positive regulation of insulin secretion
GO:0032869 ISS cellular response to insulin stimulus
GO:0042593 IMP glucose homeostasis
GO:0044281 TAS small molecule metabolic process
GO:0044320 ISS cellular response to leptin stimulus
GO:0045721 IMP negative regulation of gluconeogenesis
GO:0045725 IMP positive regulation of glycogen biosynthetic process
GO:0050796 IMP regulation of insulin secretion
GO:0051594 IMP detection of glucose
GO:0055085 TAS transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102920 Gck-004 protein_coding Mus_musculus 0 1672
ENSMUST00000109822 Gck-002 protein_coding Mus_musculus 0 1670
ENSMUST00000109823 Gck-001 protein_coding Mus_musculus 0 1670
ENSDART00000129772 gck-201 protein_coding Danio_rerio 0 508
ENSDART00000085559 gck-001 protein_coding Danio_rerio 0 508

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