C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tyrosine kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000525621 TYK2-001 ENSG00000105397 9606 - 19:10350533-10380676 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000525621
Transcript ID Adipose Adrenal Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000525621 7.457±0.00 8.881±0.00 1.660±0.00 3.297±0.00 2.917±2.29 3.106±2.29 2.766±2.41 8.036±0.00 10.009±0.00 5.145±2.55 5.031±0.36 3.041±1.75

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004GI CIL_0004GI_0001 CGP 19:10350529-10420121

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005131 IPI growth hormone receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0006468 IEA:TAS protein phosphorylation
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0031702 IEA type 1 angiotensin receptor binding
GO:0035556 IEA intracellular signal transduction
GO:0060337 TAS type I interferon signaling pathway
GO:0060338 TAS regulation of type I interferon-mediated signaling pathway
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000001036 Tyk2-201 protein_coding Mus_musculus 0 2555

Loading