C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: AXL receptor tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000002677 Axl-001 ENSMUSG00000002602 10090 - 7:25757273-25788687 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002677
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002677 39.771±13.37 13.565±5.31 42.450±1.09 5.261±0.50 43.775±6.55 19.452±1.41 18.482±1.74 12.451±1.67 5.237±1.84 37.930±3.77 4.654±1.13 59.684±17.56 5.836±3.62 9.314±0.80

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TR CIL_0008TR_0002 VISTA 7:25324415-25925712
CIL_0006UR CIL_0006UR_0002 CGP 7:25757273-25816913

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001764 IGI neuron migration
GO:0001779 IGI natural killer cell differentiation
GO:0001786 IEA phosphatidylserine binding
GO:0001961 IEA positive regulation of cytokine-mediated signaling pathway
GO:0001974 IMP blood vessel remodeling
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0006909 IGI phagocytosis
GO:0006954 IMP inflammatory response
GO:0007167 IGI enzyme linked receptor protein signaling pathway
GO:0007283 IGI spermatogenesis
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021885 IGI forebrain cell migration
GO:0030154 IEA cell differentiation
GO:0030168 IMP platelet activation
GO:0031100 IEA organ regeneration
GO:0031668 IDA cellular response to extracellular stimulus
GO:0032036 IEA myosin heavy chain binding
GO:0032689 IEA negative regulation of interferon-gamma production
GO:0032720 IGI negative regulation of tumor necrosis factor production
GO:0032825 IEA positive regulation of natural killer cell differentiation
GO:0032940 IMP secretion by cell
GO:0034101 IGI erythrocyte homeostasis
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0035457 IEA cellular response to interferon-alpha
GO:0042698 IGI ovulation cycle
GO:0043066 IMP negative regulation of apoptotic process
GO:0043277 IGI apoptotic cell clearance
GO:0043491 IGI protein kinase B signaling
GO:0043524 IGI negative regulation of neuron apoptotic process
GO:0043548 IEA phosphatidylinositol 3-kinase binding
GO:0045087 IEA innate immune response
GO:0046982 IPI protein heterodimerization activity
GO:0048469 IEA cell maturation
GO:0051250 IGI negative regulation of lymphocyte activation
GO:0051897 IMP positive regulation of protein kinase B signaling
GO:0060068 IGI vagina development
GO:0070062 IEA extracellular vesicular exosome
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0097028 IEA dendritic cell differentiation
GO:2000669 IEA negative regulation of dendritic cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000301178 AXL-001 protein_coding Homo_sapiens 0 2988
ENST00000359092 AXL-002 protein_coding Homo_sapiens 0 2859
ENST00000593513 AXL-004 protein_coding Homo_sapiens 0 2459
ENST00000599659 AXL-003 retained_intron Homo_sapiens 0 1395

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