C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: AXL receptor tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000359092 AXL-002 ENSG00000167601 9606 + 19:41219235-41260294 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonHeartKidneyLungMuscleOvaryPlacentaENST00000359092
Transcript ID Adrenal Breast Colon Heart Kidney Lung Muscle Ovary Placenta
ENST00000359092 2.892±0.00 1.742±0.00 9.405±0.00 0.556±0.00 1.451±0.00 5.448±0.00 1.985±0.00 8.974±0.00 4.377±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TR CIL_0008TR_0001 VISTA 19:41131081-41732986

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001786 IDA phosphatidylserine binding
GO:0001961 IDA positive regulation of cytokine-mediated signaling pathway
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005615 IDA extracellular space
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006909 IDA phagocytosis
GO:0007165 TAS signal transduction
GO:0009986 IDA cell surface
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0032689 IDA negative regulation of interferon-gamma production
GO:0032825 IDA positive regulation of natural killer cell differentiation
GO:0035457 IDA cellular response to interferon-alpha
GO:0045087 IEA innate immune response
GO:0048469 IEP cell maturation
GO:0070062 IDA extracellular vesicular exosome
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0097028 IEP dendritic cell differentiation
GO:2000669 IDA negative regulation of dendritic cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000085948 Axl-002 protein_coding Mus_musculus 0 2955
ENSMUST00000002677 Axl-001 protein_coding Mus_musculus 0 2859
ENSMUST00000132989 Axl-003 retained_intron Mus_musculus 0 1823
ENSMUST00000124442 Axl-008 retained_intron Mus_musculus 0 706
ENSMUST00000137211 Axl-007 retained_intron Mus_musculus 0 551
ENSMUST00000132038 Axl-009 protein_coding Mus_musculus 0 460

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