C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase inhibitor 1B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000003115 Cdkn1b-002 ENSMUSG00000003031 10090 + 6:134920401-134925513 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003115
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003115 11.492±4.45 36.208±2.52 11.953±0.43 13.390±7.64 27.090±10.61 26.432±4.92 6.786±2.17 14.098±2.16 8.007±1.70 23.636±3.17 10.410±0.47 35.329±7.88 9.067±2.09 2.035±0.80

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000KC CIL_0000KC_0002 CGP 6:134869093-134925513
CIL_0000KD CIL_0000KD_0002 CGP 6:134920401-134986836

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IDA G1/S transition of mitotic cell cycle
GO:0004861 IDA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005829 IDA cytosol
GO:0006813 IGI potassium ion transport
GO:0007050 IDA cell cycle arrest
GO:0007605 IMP sensory perception of sound
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0031116 IGI positive regulation of microtubule polymerization
GO:0043066 IMP negative regulation of apoptotic process
GO:0045736 IDA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0048839 IMP inner ear development
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0051271 IDA negative regulation of cellular component movement
GO:0060770 IMP negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0071236 IDA cellular response to antibiotic
GO:0071285 ISO cellular response to lithium ion
GO:0071407 IDA cellular response to organic cyclic compound

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000228872 CDKN1B-001 protein_coding Homo_sapiens 0 1315
ENST00000396340 CDKN1B-003 protein_coding Homo_sapiens 0 564
ENST00000442489 CDKN1B-002 protein_coding Homo_sapiens 0 492
ENST00000477087 CDKN1B-004 processed_transcript Homo_sapiens 0 379

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