C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: G protein-coupled receptor kinase 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000003313 Grk5-201 ENSMUSG00000003228 10090 + 19:60889749-61092553 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003313
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003313 3.760±1.88 1.393±0.64 3.766±0.33 1.632±0.84 2.388±1.07 1.377±0.66 1.186±0.26 1.283±0.71 0.647±0.26 3.687±1.77 1.010±0.30 2.040±1.40 1.639±0.95 0.769±0.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005VT CIL_0005VT_0002 CGP 19:60864051-61092553

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004703 IEA G-protein coupled receptor kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 ISS plasma membrane
GO:0006915 IEA apoptotic process
GO:0007217 IEA tachykinin receptor signaling pathway
GO:0008289 IEA lipid binding
GO:0016055 IEA Wnt signaling pathway
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043066 ISS negative regulation of apoptotic process
GO:0046777 ISS protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000369108 GRK5-003 retained_intron Homo_sapiens 0 828
ENST00000392870 GRK5-002 protein_coding Homo_sapiens 0 2892

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