C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: G protein-coupled receptor kinase 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000392870 GRK5-002 ENSG00000198873 9606 + 10:119207589-119455619 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000392870
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000392870 10.963±0.00 13.819±0.00 0.351±0.00 2.142±1.23 7.784±3.62 14.892±13.35 6.426±4.64 2.749±1.72 2.961±0.70 34.948±32.76 2.626±1.94 16.069±9.38 10.387±1.23 5.833±3.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005VT CIL_0005VT_0001 CGP 10:119167703-119459742

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004703 IEA G-protein coupled receptor kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005080 TAS protein kinase C binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005543 TAS phospholipid binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007188 TAS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007217 IDA tachykinin receptor signaling pathway
GO:0008277 TAS:IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0016055 IEA Wnt signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043066 IDA negative regulation of apoptotic process
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000003313 Grk5-201 protein_coding Mus_musculus 0 2892

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