C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transforming growth factor, beta 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000003687 Tgfb3-201 ENSMUSG00000021253 10090 - 12:86056744-86079041 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003687
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003687 12.596±1.72 5.311±0.39 21.238±2.93 4.816±2.05 13.717±2.98 6.271±0.54 5.920±0.43 1.397±0.23 0.899±0.54 15.800±0.82 7.827±0.44 21.337±5.08 16.622±5.43 2.128±1.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004WU CIL_0004WU_0002 CGP 12:85815448-86061893
CIL_000061 CIL_000061_0002 CGP 12:85824659-86079041

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0001666 IEA response to hypoxia
GO:0001701 IMP in utero embryonic development
GO:0005114 IEA type II transforming growth factor beta receptor binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007184 IEA SMAD protein import into nucleus
GO:0007435 IEA salivary gland morphogenesis
GO:0007565 IEA female pregnancy
GO:0007568 IEA aging
GO:0008083 IEA growth factor activity
GO:0008156 IEA negative regulation of DNA replication
GO:0008285 IDA negative regulation of cell proliferation
GO:0009887 IMP organ morphogenesis
GO:0009986 IEA cell surface
GO:0010718 IMP positive regulation of epithelial to mesenchymal transition
GO:0010862 IMP positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010936 IEA negative regulation of macrophage cytokine production
GO:0016049 IEA cell growth
GO:0022601 IEA menstrual cycle phase
GO:0030141 IEA secretory granule
GO:0030315 IEA T-tubule
GO:0030501 IEA positive regulation of bone mineralization
GO:0030512 IEA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030879 IDA mammary gland development
GO:0031012 IDA extracellular matrix
GO:0032570 IEA response to progesterone
GO:0032967 IEA positive regulation of collagen biosynthetic process
GO:0034616 IEA response to laminar fluid shear stress
GO:0034713 IEA type I transforming growth factor beta receptor binding
GO:0042060 IEA wound healing
GO:0042802 IEA identical protein binding
GO:0043025 IEA neuronal cell body
GO:0043065 IMP positive regulation of apoptotic process
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0043627 IEA response to estrogen
GO:0043932 IEA ossification involved in bone remodeling
GO:0045216 IEA cell-cell junction organization
GO:0045740 IEA positive regulation of DNA replication
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048286 IMP lung alveolus development
GO:0048565 IEA digestive tract development
GO:0048702 IEA embryonic neurocranium morphogenesis
GO:0048839 IEA inner ear development
GO:0050431 IEA transforming growth factor beta binding
GO:0050714 IEA positive regulation of protein secretion
GO:0051491 IMP positive regulation of filopodium assembly
GO:0051781 IEA positive regulation of cell division
GO:0060021 IMP palate development
GO:0060325 IEP face morphogenesis
GO:0060364 IEA frontal suture morphogenesis
GO:0060391 IMP positive regulation of SMAD protein import into nucleus
GO:0070483 IEA detection of hypoxia
GO:0071363 IDA cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000238682 TGFB3-001 protein_coding Homo_sapiens 0 2217
ENST00000554980 TGFB3-003 retained_intron Homo_sapiens 0 1131
ENST00000555193 TGFB3-006 processed_transcript Homo_sapiens 0 673
ENST00000556285 TGFB3-002 protein_coding Homo_sapiens 0 1339
ENST00000556674 TGFB3-005 processed_transcript Homo_sapiens 0 468
ENST00000557493 TGFB3-007 processed_transcript Homo_sapiens 0 603

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