C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transforming growth factor, beta 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000238682 TGFB3-001 ENSG00000119699 9606 - 14:75958202-75981191 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000238682
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000238682 3.325±0.00 16.676±0.00 4.578±3.91 3.754±1.50 3.961±3.46 2.946±0.00 4.117±0.00 1.989±1.16 15.005±14.08 5.456±4.57 2.368±0.72 9.781±2.59 9.429±6.50

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0001666 IDA response to hypoxia
GO:0001701 ISS in utero embryonic development
GO:0002576 TAS platelet degranulation
GO:0005114 IDA type II transforming growth factor beta receptor binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IC plasma membrane
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007184 IEA SMAD protein import into nucleus
GO:0007435 IEP salivary gland morphogenesis
GO:0007565 IEA female pregnancy
GO:0007568 IEA aging
GO:0007596 TAS blood coagulation
GO:0008083 IEA growth factor activity
GO:0008156 IMP negative regulation of DNA replication
GO:0008285 ISS negative regulation of cell proliferation
GO:0009887 IEA organ morphogenesis
GO:0009986 IEA cell surface
GO:0010718 ISS positive regulation of epithelial to mesenchymal transition
GO:0010862 ISS positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010936 IDA negative regulation of macrophage cytokine production
GO:0016049 IEA cell growth
GO:0022601 IEP menstrual cycle phase
GO:0030141 IEA secretory granule
GO:0030168 TAS platelet activation
GO:0030198 TAS extracellular matrix organization
GO:0030315 IEA T-tubule
GO:0030501 IEP positive regulation of bone mineralization
GO:0030512 IEA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030879 ISS mammary gland development
GO:0031012 IDA extracellular matrix
GO:0031093 TAS platelet alpha granule lumen
GO:0032570 IDA response to progesterone
GO:0032967 IMP positive regulation of collagen biosynthetic process
GO:0034616 IEA response to laminar fluid shear stress
GO:0034713 IDA type I transforming growth factor beta receptor binding
GO:0040007 IEA growth
GO:0042060 IEA wound healing
GO:0042476 NAS odontogenesis
GO:0042802 IDA identical protein binding
GO:0043025 IEA neuronal cell body
GO:0043065 ISS positive regulation of apoptotic process
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0043627 IEA response to estrogen
GO:0043932 IEP ossification involved in bone remodeling
GO:0045216 IDA cell-cell junction organization
GO:0045740 IMP positive regulation of DNA replication
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048286 ISS lung alveolus development
GO:0048565 IEA digestive tract development
GO:0048702 IEA embryonic neurocranium morphogenesis
GO:0048839 IEA inner ear development
GO:0050431 IDA transforming growth factor beta binding
GO:0050714 IDA positive regulation of protein secretion
GO:0051491 ISS positive regulation of filopodium assembly
GO:0051781 IEA positive regulation of cell division
GO:0060021 ISS palate development
GO:0060325 IMP face morphogenesis
GO:0060364 IEA frontal suture morphogenesis
GO:0060391 ISS positive regulation of SMAD protein import into nucleus
GO:0070483 IDA detection of hypoxia
GO:0071363 IEA cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000003687 Tgfb3-201 protein_coding Mus_musculus 0 2217

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