C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hyperpolarization-activated, cyclic nucleotide-gated K+ 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000006991 Hcn1-001 ENSMUSG00000021730 10090 + 13:117602480-117976802 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006991
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006991 0.016±0.01 0.059±0.04 5.480±1.72 0.567±0.09 0.156±0.06 0.039±0.01 0.847±0.11 0.016±0.01 0.012±0.01 0.362±0.06 0.025±0.01 1.264±0.43 0.028±0.02 0.549±0.29

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005222 IMP intracellular cAMP activated cation channel activity
GO:0005248 IEA voltage-gated sodium channel activity
GO:0005249 IBA voltage-gated potassium channel activity
GO:0005515 IPI protein binding
GO:0005886 IEA plasma membrane
GO:0005887 IBA integral component of plasma membrane
GO:0030424 IDA axon
GO:0030425 IDA dendrite
GO:0030552 IDA cAMP binding
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0042391 IBA regulation of membrane potential
GO:0042802 IPI identical protein binding
GO:0045176 IMP apical protein localization
GO:0046549 IMP retinal cone cell development
GO:0071320 IMP cellular response to cAMP
GO:0071805 IBA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000136390 hcn2b-001 protein_coding Danio_rerio 0 909
ENSDART00000131044 HCN2 (2 of 2)-201 protein_coding Danio_rerio 0 845
ENST00000303230 HCN1-001 protein_coding Homo_sapiens 0 2761

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