C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitochondrial calcium uniporter
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000009791 Mcu-004 ENSMUSG00000009647 10090 - 10:59448597-59458160 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainOvaryTestisENSMUST00000009791
Transcript ID Brain Ovary Testis
ENSMUST00000009791 2.583±0.00 1.980±0.00 5.407±0.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QA CIL_0008QA_0002 VISTA 10:59142760-59744333
CIL_0006SA CIL_0006SA_0002 CGP 10:59422958-59616692

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005262 ISS calcium channel activity
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005743 ISS mitochondrial inner membrane
GO:0006851 IMP mitochondrial calcium ion transport
GO:0019722 ISS calcium-mediated signaling
GO:0031305 ISS integral component of mitochondrial inner membrane
GO:0032024 ISS positive regulation of insulin secretion
GO:0034704 IDA calcium channel complex
GO:0035786 ISS protein complex oligomerization
GO:0036444 ISO calcium ion transmembrane import into mitochondrion
GO:0042593 ISS glucose homeostasis
GO:0042802 IPI identical protein binding
GO:0051561 IMP positive regulation of mitochondrial calcium ion concentration
GO:1990246 ISS uniplex complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000357157 MCU-001 protein_coding Homo_sapiens 0 601
ENST00000373053 MCU-002 protein_coding Homo_sapiens 0 747
ENST00000536019 MCU-201 protein_coding Homo_sapiens 0 747
ENST00000603118 MCU-009 processed_transcript Homo_sapiens 0 608
ENST00000605416 MCU-010 processed_transcript Homo_sapiens 0 627
ENST00000605597 MCU-006 nonsense_mediated_decay Homo_sapiens 0 747
ENST00000622066 MCU-202 protein_coding Homo_sapiens 0 601

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