C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adenosine A2b receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000304222 ADORA2B-001 ENSG00000170425 9606 + 17:15944917-15975746 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartLiverLungOvaryPlacentaENST00000304222
Transcript ID Adrenal Bladder Brain Breast Colon Heart Liver Lung Ovary Placenta
ENST00000304222 0.148±0.00 0.627±0.00 1.736±0.15 0.543±0.02 2.605±1.43 0.173±0.10 0.575±0.00 1.630±1.42 1.852±0.41 3.933±2.57

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XH CIL_0002XH_0001 CGP 17:15944917-15999717

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 TAS activation of MAPK activity
GO:0001609 IEA G-protein coupled adenosine receptor activity
GO:0001973 IEA adenosine receptor signaling pathway
GO:0002882 IEA positive regulation of chronic inflammatory response to non-antigenic stimulus
GO:0004930 IEA G-protein coupled receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006968 TAS cellular defense response
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007189 IEA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 TAS activation of adenylate cyclase activity
GO:0007254 TAS JNK cascade
GO:0007588 TAS excretion
GO:0010575 IEA positive regulation vascular endothelial growth factor production
GO:0016021 IEA integral component of membrane
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0030828 IEA positive regulation of cGMP biosynthetic process
GO:0031284 IEA positive regulation of guanylate cyclase activity
GO:0031668 IEA cellular response to extracellular stimulus
GO:0032722 IEA positive regulation of chemokine production
GO:0032755 IEA positive regulation of interleukin-6 production
GO:0043306 IEA positive regulation of mast cell degranulation
GO:0060087 IEA relaxation of vascular smooth muscle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018644 Adora2b-001 protein_coding Mus_musculus 0 1332

Loading