C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000019076 Map2k3-001 ENSMUSG00000018932 10090 + 11:60932033-60952811 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000019076
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000019076 17.626±4.63 15.838±2.67 19.089±0.76 3.881±0.63 18.196±11.45 17.093±4.59 20.385±3.42 15.053±2.77 22.152±13.25 15.836±4.91 66.984±8.06 13.787±3.97 27.427±5.80 14.736±4.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00013Z CIL_00013Z_0002 CGP 11:60902246-60952811
CIL_000142 CIL_000142_0002 CGP 11:60932033-61071131

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IMP MAPK cascade
GO:0000187 IMP activation of MAPK activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004708 IMP MAP kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0006954 IMP inflammatory response
GO:0016020 IEA membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019901 IPI protein kinase binding
GO:0042035 IMP regulation of cytokine biosynthetic process
GO:0045860 IEA positive regulation of protein kinase activity
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0060048 IMP cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000316920 MAP2K3-013 protein_coding Homo_sapiens 0 1354
ENST00000342679 MAP2K3-001 protein_coding Homo_sapiens 0 1515
ENST00000361818 MAP2K3-201 protein_coding Homo_sapiens 0 1413
ENST00000395491 MAP2K3-002 nonsense_mediated_decay Homo_sapiens 0 1415
ENST00000477540 MAP2K3-009 retained_intron Homo_sapiens 0 420
ENST00000479129 MAP2K3-006 nonsense_mediated_decay Homo_sapiens 0 300
ENST00000496046 MAP2K3-004 nonsense_mediated_decay Homo_sapiens 0 730
ENST00000526076 MAP2K3-016 protein_coding Homo_sapiens 0 684
ENST00000527123 MAP2K3-014 protein_coding Homo_sapiens 0 246
ENST00000583508 MAP2K3-017 retained_intron Homo_sapiens 0 257
ENST00000613338 MAP2K3-202 protein_coding Homo_sapiens 0 1415

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