C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: apoptotic peptidase activating factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000359972 APAF1-001 ENSG00000120868 9606 + 12:98645300-98735433 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartENST00000359972
Transcript ID Heart
ENST00000359972 0.217±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090D CIL_00090D_0001 VISTA 12:98189717-98793261
CIL_0000T8 CIL_0000T8_0002 CGP 12:98645141-99984654

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 TAS nucleotide binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006915 TAS apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007399 TAS nervous system development
GO:0008635 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0008656 NAS cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0042981 TAS:IEA regulation of apoptotic process
GO:0043065 TAS positive regulation of apoptotic process
GO:0043293 TAS apoptosome
GO:0043531 IEA ADP binding
GO:0070062 IDA extracellular vesicular exosome
GO:0072432 TAS response to G1 DNA damage checkpoint signaling
GO:0097193 TAS intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000162618 Apaf1-003 protein_coding Mus_musculus 0 2796
ENSMUST00000020157 Apaf1-001 protein_coding Mus_musculus 0 2545
ENSMUST00000159110 Apaf1-002 protein_coding Mus_musculus 0 2545
ENSMUST00000160725 Apaf1-008 retained_intron Mus_musculus 3e-31 143
ENSMUST00000105321 Nfic-001 protein_coding Mus_musculus 0.0000002 64
ENSMUST00000091246 Flcn-005 protein_coding Mus_musculus 0.00001 58
ENSMUST00000148151 Flcn-003 retained_intron Mus_musculus 0.00001 58
ENSMUST00000102697 Flcn-004 protein_coding Mus_musculus 0.00001 58

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