C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dihydrofolate reductase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022218 Dhfr-201 ENSMUSG00000021707 10090 + 13:92354783-92389053 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022218
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022218 0.839±0.26 1.698±0.54 0.982±0.09 2.169±1.02 0.899±0.25 1.253±0.34 0.393±0.08 8.671±0.61 7.737±3.29 0.674±0.10 0.521±0.07 2.006±0.36 3.198±1.82 0.777±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002ZB CIL_0002ZB_0002 CGP 13:92354783-92441658

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003729 ISS mRNA binding
GO:0004146 ISS dihydrofolate reductase activity
GO:0005829 TAS cytosol
GO:0006545 IEA glycine biosynthetic process
GO:0006730 IEA one-carbon metabolic process
GO:0008144 ISS drug binding
GO:0009165 IEA nucleotide biosynthetic process
GO:0031427 IEA response to methotrexate
GO:0035094 IEA response to nicotine
GO:0046452 IEA dihydrofolate metabolic process
GO:0046653 ISS tetrahydrofolate metabolic process
GO:0046654 IEA tetrahydrofolate biosynthetic process
GO:0050661 IEA NADP binding
GO:0051871 IEA dihydrofolic acid binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000314636 DHFRL1-002 protein_coding Homo_sapiens 0 684
ENST00000394221 DHFRL1-001 protein_coding Homo_sapiens 0 684
ENST00000406944 RP11-448N11.1-001 processed_pseudogene Homo_sapiens 0 344
ENST00000439211 DHFR-001 protein_coding Homo_sapiens 0 704
ENST00000455595 AC098817.5-001 processed_pseudogene Homo_sapiens 0 518
ENST00000461173 DHFRL1-003 nonsense_mediated_decay Homo_sapiens 0 684
ENST00000496983 DHFRL1-004 protein_coding Homo_sapiens 0 435
ENST00000504396 DHFR-003 protein_coding Homo_sapiens 0 560
ENST00000505337 DHFR-006 protein_coding Homo_sapiens 0 704
ENST00000508282 DHFR-007 retained_intron Homo_sapiens 0 614
ENST00000511032 DHFR-005 protein_coding Homo_sapiens 0 453
ENST00000513048 DHFR-004 processed_transcript Homo_sapiens 6e-40 169
ENST00000513314 DHFR-008 retained_intron Homo_sapiens 0 209
ENST00000579682 DHFRP1-001 processed_pseudogene Homo_sapiens 0 686
ENST00000619045 DHFRL1-201 protein_coding Homo_sapiens 0 684

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