C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: spastin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000024869 Spast-201 ENSMUSG00000024068 10090 + 17:74338987-74391113 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024869
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024869 4.047±1.10 7.764±3.88 4.522±0.40 19.209±9.54 3.328±1.13 3.741±0.98 2.126±0.64 2.207±0.12 3.636±0.56 3.885±0.54 3.354±0.59 7.086±1.66 5.337±0.51 9.048±0.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000VL CIL_0000VL_0002 CGP 17:74299474-74391113
CIL_0000VK CIL_0000VK_0002 CGP 17:74338987-74424229

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001578 ISS microtubule bundle formation
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0005768 ISS endosome
GO:0005783 ISS endoplasmic reticulum
GO:0005813 IEA centrosome
GO:0005874 IEA microtubule
GO:0006200 IEA ATP catabolic process
GO:0006888 ISS ER to Golgi vesicle-mediated transport
GO:0007109 ISS cytokinesis, completion of separation
GO:0007409 IEA axonogenesis
GO:0008017 ISS microtubule binding
GO:0008568 ISS microtubule-severing ATPase activity
GO:0015630 IDA microtubule cytoskeleton
GO:0016021 IEA integral component of membrane
GO:0030496 ISS midbody
GO:0031117 IEA positive regulation of microtubule depolymerization
GO:0031410 IEA cytoplasmic vesicle
GO:0034214 ISS protein hexamerization
GO:0043014 ISS alpha-tubulin binding
GO:0048487 ISS beta-tubulin binding
GO:0051013 ISS microtubule severing
GO:0051260 ISS protein homooligomerization
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000315285 SPAST-001 protein_coding Homo_sapiens 0 2418
ENST00000345662 SPAST-002 protein_coding Homo_sapiens 0 1513
ENST00000615843 SPAST-201 protein_coding Homo_sapiens 0 2418
ENST00000621856 SPAST-003 protein_coding Homo_sapiens 0 2135

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