C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: spastin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000345662 SPAST-002 ENSG00000021574 9606 + 2:32063611-32157636 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000345662
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000345662 0.579±0.00 1.034±0.00 3.598±0.06 1.525±0.88 1.457±0.00 0.638±0.13 0.586±0.10 1.286±0.08 1.049±0.52 2.517±1.53 1.559±0.46 0.786±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000VL CIL_0000VL_0001 CGP 2:31867809-32157637
CIL_0000VK CIL_0000VK_0001 CGP 2:32063611-32224379

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001578 IDA microtubule bundle formation
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005768 IDA endosome
GO:0005783 IDA endoplasmic reticulum
GO:0005813 IEA centrosome
GO:0005874 IEA microtubule
GO:0006200 IEA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0006888 IMP ER to Golgi vesicle-mediated transport
GO:0007109 IMP cytokinesis, completion of separation
GO:0007409 IEA axonogenesis
GO:0008017 IDA microtubule binding
GO:0008219 IEA cell death
GO:0008568 IDA:IEA microtubule-severing ATPase activity
GO:0009378 IEA four-way junction helicase activity
GO:0015630 IDA microtubule cytoskeleton
GO:0016021 IEA integral component of membrane
GO:0030496 IDA midbody
GO:0031117 IEA positive regulation of microtubule depolymerization
GO:0031410 IDA cytoplasmic vesicle
GO:0034214 IDA protein hexamerization
GO:0043014 IPI alpha-tubulin binding
GO:0048487 IPI beta-tubulin binding
GO:0051013 IDA microtubule severing
GO:0051260 IDA protein homooligomerization
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000024869 Spast-201 protein_coding Mus_musculus 0 1513

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