C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: colony stimulating factor 1 receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025523 Csf1r-001 ENSMUSG00000024621 10090 + 18:61105572-61131134 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025523
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025523 35.388±5.50 13.710±0.64 21.322±0.02 6.480±5.23 45.968±4.86 17.579±1.47 8.090±2.24 11.337±4.37 13.688±5.35 33.865±3.72 2.175±0.53 18.463±3.25 113.331±81.69 1.652±0.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00091Q CIL_00091Q_0002 VISTA 18:60604549-61207221

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005011 IMP macrophage colony-stimulating factor receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 IDA plasma membrane
GO:0006954 IEA inflammatory response
GO:0007169 IMP transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008284 IMP positive regulation of cell proliferation
GO:0008360 IMP regulation of cell shape
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019903 IPI protein phosphatase binding
GO:0019955 IPI cytokine binding
GO:0030316 IMP osteoclast differentiation
GO:0030335 IMP positive regulation of cell migration
GO:0031529 IMP ruffle organization
GO:0036006 IMP cellular response to macrophage colony-stimulating factor stimulus
GO:0038145 IMP macrophage colony-stimulating factor signaling pathway
GO:0042517 IMP positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042803 IPI protein homodimerization activity
GO:0043235 IDA receptor complex
GO:0045087 IEA innate immune response
GO:0045124 ISS regulation of bone resorption
GO:0046488 IMP phosphatidylinositol metabolic process
GO:0046777 IDA protein autophosphorylation
GO:0048015 IMP phosphatidylinositol-mediated signaling
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0071345 IMP cellular response to cytokine stimulus
GO:0071902 IMP positive regulation of protein serine/threonine kinase activity
GO:2000249 IMP regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000286301 CSF1R-001 protein_coding Homo_sapiens 0 2091
ENST00000502660 CSF1R-003 retained_intron Homo_sapiens 0 296
ENST00000504875 CSF1R-002 nonsense_mediated_decay Homo_sapiens 0 1024
ENST00000515068 CSF1R-007 nonsense_mediated_decay Homo_sapiens 0 566
ENST00000543093 CSF1R-201 protein_coding Homo_sapiens 0 296

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