C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: colony stimulating factor 1 receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000286301 CSF1R-001 ENSG00000182578 9606 - 5:150053291-150113372 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverOvaryPlacentaENST00000286301
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Ovary Placenta
ENST00000286301 2.281±0.00 6.943±0.00 0.428±0.00 4.040±2.02 1.070±0.00 1.295±0.00 0.682±0.00 0.846±0.00 1.689±0.00 5.509±0.00 29.212±12.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00091Q CIL_00091Q_0001 VISTA 5:150006686-150608670

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005011 IMP macrophage colony-stimulating factor receptor activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006954 TAS inflammatory response
GO:0007165 TAS signal transduction
GO:0007169 ISS:IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 TAS multicellular organismal development
GO:0008283 IMP cell proliferation
GO:0008284 IMP positive regulation of cell proliferation
GO:0008360 IMP regulation of cell shape
GO:0009986 ISS cell surface
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019221 IMP cytokine-mediated signaling pathway
GO:0019903 IEA protein phosphatase binding
GO:0019955 ISS cytokine binding
GO:0030097 IMP hemopoiesis
GO:0030224 TAS monocyte differentiation
GO:0030225 TAS macrophage differentiation
GO:0030316 ISS osteoclast differentiation
GO:0030335 ISS positive regulation of cell migration
GO:0031529 ISS ruffle organization
GO:0036006 IMP cellular response to macrophage colony-stimulating factor stimulus
GO:0038145 IEA macrophage colony-stimulating factor signaling pathway
GO:0042517 ISS positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042803 ISS protein homodimerization activity
GO:0043235 ISS receptor complex
GO:0045087 IEA innate immune response
GO:0045124 ISS regulation of bone resorption
GO:0045217 IMP cell-cell junction maintenance
GO:0046488 ISS phosphatidylinositol metabolic process
GO:0046777 IDA protein autophosphorylation
GO:0048015 ISS phosphatidylinositol-mediated signaling
GO:0060603 TAS mammary gland duct morphogenesis
GO:0061098 IMP positive regulation of protein tyrosine kinase activity
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0071345 ISS cellular response to cytokine stimulus
GO:0071902 ISS positive regulation of protein serine/threonine kinase activity
GO:0090197 IMP positive regulation of chemokine secretion
GO:2000147 IMP positive regulation of cell motility
GO:2000249 ISS regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000115268 Csf1r-201 protein_coding Mus_musculus 0 2091
ENSMUST00000025523 Csf1r-001 protein_coding Mus_musculus 0 2091
ENSMUST00000115274 Pdgfrb-002 protein_coding Mus_musculus 2e-30 139
ENSMUST00000025522 Pdgfrb-001 protein_coding Mus_musculus 2e-30 139

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