C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Janus kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025705 Jak2-201 ENSMUSG00000024789 10090 + 19:29251828-29313080 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastMuscleOvaryPlacentaENSMUST00000025705
Transcript ID Brain Breast Muscle Ovary Placenta
ENSMUST00000025705 5.034±0.00 1.443±0.00 2.755±0.00 4.617±2.31 5.560±0.73

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000NF CIL_0000NF_0002 CGP 19:29101375-29313080
CIL_0000NG CIL_0000NG_0002 CGP 19:29251828-29325356

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004713 IDA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005143 IPI interleukin-12 receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 TAS cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005901 IDA caveola
GO:0007167 IDA enzyme linked receptor protein signaling pathway
GO:0007259 IMP JAK-STAT cascade
GO:0007260 IMP tyrosine phosphorylation of STAT protein
GO:0007262 IDA STAT protein import into nucleus
GO:0008285 IMP negative regulation of cell proliferation
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030099 IMP myeloid cell differentiation
GO:0030154 IMP cell differentiation
GO:0034050 IDA host programmed cell death induced by symbiont
GO:0035556 IDA intracellular signal transduction
GO:0042393 IEA histone binding
GO:0043066 IDA negative regulation of apoptotic process
GO:0043392 IDA negative regulation of DNA binding
GO:0045121 IDA membrane raft
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046677 ISO response to antibiotic
GO:0061180 IMP mammary gland epithelium development
GO:0097191 IDA extrinsic apoptotic signaling pathway
GO:2001235 IMP positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000016019 jak2b-201 protein_coding Danio_rerio 0 745
ENSDART00000122405 jak2b-202 protein_coding Danio_rerio 0 745
ENST00000381652 JAK2-001 protein_coding Homo_sapiens 0 4189

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