C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BCL2-associated agonist of cell death
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025910 Bad-001 ENSMUSG00000024959 10090 + 19:6941861-6951898 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonKidneyLiverMuscleOvaryPlacentaENSMUST00000025910
Transcript ID Bladder Brain Colon Kidney Liver Muscle Ovary Placenta
ENSMUST00000025910 7.877±1.16 10.616±1.73 7.855±0.00 8.185±0.43 3.681±0.99 2.649±0.37 9.402±2.10 6.917±2.69

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0001836 IMP release of cytochrome c from mitochondria
GO:0005515 IPI protein binding
GO:0005543 ISS phospholipid binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 ISS mitochondrial outer membrane
GO:0005829 IDA cytosol
GO:0006007 IMP glucose catabolic process
GO:0006915 IEA apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008283 IDA cell proliferation
GO:0008289 ISS lipid binding
GO:0008625 IMP extrinsic apoptotic signaling pathway via death domain receptors
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008656 IDA cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0009725 IEA response to hormone
GO:0009749 IEA response to glucose
GO:0010033 IEA response to organic substance
GO:0010918 IMP positive regulation of mitochondrial membrane potential
GO:0014070 IEA response to organic cyclic compound
GO:0019050 IDA suppression by virus of host apoptotic process
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019901 IEA protein kinase binding
GO:0019903 IPI protein phosphatase binding
GO:0030346 IEA protein phosphatase 2B binding
GO:0032024 IMP positive regulation of insulin secretion
GO:0032355 IEA response to estradiol
GO:0032570 IEA response to progesterone
GO:0033133 IMP positive regulation of glucokinase activity
GO:0033574 IEA response to testosterone
GO:0034201 IEA response to oleic acid
GO:0035774 IMP positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0042593 IMP glucose homeostasis
GO:0042981 IDA regulation of apoptotic process
GO:0043065 ISO positive regulation of apoptotic process
GO:0043200 IEA response to amino acid
GO:0043280 ISS positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043281 IMP regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043422 IEA protein kinase B binding
GO:0044342 IMP type B pancreatic cell proliferation
GO:0045471 IEA response to ethanol
GO:0045579 IMP positive regulation of B cell differentiation
GO:0045582 IMP positive regulation of T cell differentiation
GO:0045862 IEA positive regulation of proteolysis
GO:0046031 IMP ADP metabolic process
GO:0046034 IMP ATP metabolic process
GO:0046902 ISS regulation of mitochondrial membrane permeability
GO:0046931 ISS pore complex assembly
GO:0046982 IPI protein heterodimerization activity
GO:0050679 ISS positive regulation of epithelial cell proliferation
GO:0051384 IEA response to glucocorticoid
GO:0051592 IEA response to calcium ion
GO:0060139 IDA positive regulation of apoptotic process by virus
GO:0060154 IDA cellular process regulating host cell cycle in response to virus
GO:0071247 IEA cellular response to chromate
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071310 ISO cellular response to organic substance
GO:0071316 ISS cellular response to nicotine
GO:0071396 IEP cellular response to lipid
GO:0071456 IEA cellular response to hypoxia
GO:0090200 IEA positive regulation of release of cytochrome c from mitochondria
GO:0097190 IDA apoptotic signaling pathway
GO:0097191 IEA extrinsic apoptotic signaling pathway
GO:0097192 IDA extrinsic apoptotic signaling pathway in absence of ligand
GO:0097193 ISS intrinsic apoptotic signaling pathway
GO:0097202 IEA activation of cysteine-type endopeptidase activity
GO:1901216 IEA positive regulation of neuron death
GO:2000078 IMP positive regulation of type B pancreatic cell development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000309032 BAD-001 protein_coding Homo_sapiens 0 459
ENST00000394531 BAD-003 protein_coding Homo_sapiens 2e-23 113
ENST00000394532 BAD-002 protein_coding Homo_sapiens 0 462
ENST00000411458 GPR137-006 protein_coding Homo_sapiens 0.0000000003 71
ENST00000544271 BAD-007 retained_intron Homo_sapiens 2e-23 113
ENST00000544785 BAD-008 protein_coding Homo_sapiens 3e-20 102

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