C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BCL2-associated agonist of cell death
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000394532 BAD-002 ENSG00000002330 9606 - 11:64269830-64284639 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyENST00000394532
Transcript ID Kidney
ENST00000394532 2.675±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0001836 IEA release of cytochrome c from mitochondria
GO:0005515 IPI protein binding
GO:0005543 IMP phospholipid binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 IDA mitochondrial outer membrane
GO:0005829 IDA cytosol
GO:0006007 IEA glucose catabolic process
GO:0006915 IDA apoptotic process
GO:0006919 ISS activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008283 IEA cell proliferation
GO:0008289 IDA lipid binding
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008625 IEA extrinsic apoptotic signaling pathway via death domain receptors
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008656 IDA cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0009725 IEA response to hormone
GO:0009749 IEA response to glucose
GO:0010033 IEA response to organic substance
GO:0010508 TAS positive regulation of autophagy
GO:0010918 ISS positive regulation of mitochondrial membrane potential
GO:0014070 IEA response to organic cyclic compound
GO:0019050 IEA suppression by virus of host apoptotic process
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019901 IPI protein kinase binding
GO:0019903 IEA protein phosphatase binding
GO:0030346 IEA protein phosphatase 2B binding
GO:0032024 ISS positive regulation of insulin secretion
GO:0032355 IEA response to estradiol
GO:0032570 IEA response to progesterone
GO:0033133 ISS positive regulation of glucokinase activity
GO:0033574 IEA response to testosterone
GO:0034201 IEA response to oleic acid
GO:0035774 IEA positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0042593 ISS glucose homeostasis
GO:0042981 IEA regulation of apoptotic process
GO:0043065 IMP positive regulation of apoptotic process
GO:0043200 IEA response to amino acid
GO:0043280 IDA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043281 IEA regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043422 IEA protein kinase B binding
GO:0044342 ISS type B pancreatic cell proliferation
GO:0045087 TAS innate immune response
GO:0045471 IEA response to ethanol
GO:0045579 IEA positive regulation of B cell differentiation
GO:0045582 IEA positive regulation of T cell differentiation
GO:0045862 IDA positive regulation of proteolysis
GO:0046031 ISS ADP metabolic process
GO:0046034 ISS ATP metabolic process
GO:0046902 IMP regulation of mitochondrial membrane permeability
GO:0046931 IDA pore complex assembly
GO:0046982 IEA protein heterodimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0050679 IMP positive regulation of epithelial cell proliferation
GO:0051384 IEA response to glucocorticoid
GO:0051592 IEA response to calcium ion
GO:0060139 IEA positive regulation of apoptotic process by virus
GO:0060154 IEA cellular process regulating host cell cycle in response to virus
GO:0071247 IEA cellular response to chromate
GO:0071260 IEP cellular response to mechanical stimulus
GO:0071316 IDA cellular response to nicotine
GO:0071396 IEA cellular response to lipid
GO:0071456 IEP cellular response to hypoxia
GO:0090200 IMP positive regulation of release of cytochrome c from mitochondria
GO:0097190 TAS apoptotic signaling pathway
GO:0097191 IMP extrinsic apoptotic signaling pathway
GO:0097192 IEA extrinsic apoptotic signaling pathway in absence of ligand
GO:0097193 IMP intrinsic apoptotic signaling pathway
GO:0097202 IDA activation of cysteine-type endopeptidase activity
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1901216 IEA positive regulation of neuron death
GO:2000078 ISS positive regulation of type B pancreatic cell development
GO:2001244 TAS positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025910 Bad-001 protein_coding Mus_musculus 0 462
ENSMUST00000113423 Bad-002 protein_coding Mus_musculus 0 459
ENSMUST00000113426 Bad-005 protein_coding Mus_musculus 0 294
ENSMUST00000141410 Bad-004 protein_coding Mus_musculus 0 274

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