C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BCL2-associated agonist of cell death
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000309032 BAD-001 ENSG00000002330 9606 - 11:64269834-64284669 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000309032
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000309032 23.570±0.00 27.438±0.00 12.665±8.88 17.232±15.84 17.654±15.26 13.783±12.20 33.174±0.00 9.006±7.45 18.263±17.23 10.384±0.00 18.328±17.22 74.227±36.93 51.784±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005543 IMP phospholipid binding
GO:0005739 IDA mitochondrion
GO:0005741 IDA mitochondrial outer membrane
GO:0005829 IDA cytosol
GO:0006915 IDA apoptotic process
GO:0006919 ISS activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008289 IDA lipid binding
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008656 IDA cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0010508 TAS positive regulation of autophagy
GO:0010918 ISS positive regulation of mitochondrial membrane potential
GO:0019901 IPI protein kinase binding
GO:0032024 ISS positive regulation of insulin secretion
GO:0033133 ISS positive regulation of glucokinase activity
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042593 ISS glucose homeostasis
GO:0043065 IMP positive regulation of apoptotic process
GO:0043280 IDA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044342 ISS type B pancreatic cell proliferation
GO:0045087 TAS innate immune response
GO:0045862 IDA positive regulation of proteolysis
GO:0046031 ISS ADP metabolic process
GO:0046034 ISS ATP metabolic process
GO:0046902 IMP regulation of mitochondrial membrane permeability
GO:0046931 IDA pore complex assembly
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0050679 IMP positive regulation of epithelial cell proliferation
GO:0071260 IEP cellular response to mechanical stimulus
GO:0071316 IDA cellular response to nicotine
GO:0071456 IEP cellular response to hypoxia
GO:0090200 IMP positive regulation of release of cytochrome c from mitochondria
GO:0097190 TAS apoptotic signaling pathway
GO:0097191 IMP extrinsic apoptotic signaling pathway
GO:0097193 IMP intrinsic apoptotic signaling pathway
GO:0097202 IDA activation of cysteine-type endopeptidase activity
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:2000078 ISS positive regulation of type B pancreatic cell development
GO:2001244 TAS positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000113423 Bad-002 protein_coding Mus_musculus 0 527
ENSMUST00000025910 Bad-001 protein_coding Mus_musculus 0 459
ENSMUST00000113426 Bad-005 protein_coding Mus_musculus 0 291
ENSMUST00000141410 Bad-004 protein_coding Mus_musculus 0 274

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