C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tripartite motif-containing 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000026008 Trim8-201 ENSMUSG00000025034 10090 + 19:46501648-46516444 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026008
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026008 18.651±2.21 19.939±9.80 10.005±2.89 23.455±12.67 20.276±9.73 21.847±2.80 7.457±1.12 17.129±2.57 7.216±2.39 46.263±5.35 7.719±0.39 33.953±12.91 19.513±8.27 1.121±0.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MQ CIL_0008MQ_0002 VISTA 19:46318498-46919738
CIL_00065X CIL_00065X_0002 CGP 19:46396896-46516444
CIL_0001HP CIL_0001HP_0003 CGP 19:46501648-46573085

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 NAS ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016605 IEA PML body
GO:0016874 IEA ligase activity
GO:0032897 IDA negative regulation of viral transcription
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045087 IDA innate immune response
GO:0046597 IDA negative regulation of viral entry into host cell
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity
GO:1902187 IDA negative regulation of viral release from host cell

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000302424 TRIM8-001 protein_coding Homo_sapiens 0 2639
ENST00000462202 TRIM8-003 protein_coding Homo_sapiens 0 809
ENST00000479004 TRIM8-004 processed_transcript Homo_sapiens 0 606
ENST00000487927 TRIM8-002 processed_transcript Homo_sapiens 0 998

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