C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: pancreas specific transcription factor, 1a
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000028068 Ptf1a-001 ENSMUSG00000026735 10090 + 2:19445663-19447501 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonLiverLungOvaryTestisENSMUST00000028068
Transcript ID Adipose Brain Colon Liver Lung Ovary Testis
ENSMUST00000028068 0.054±0.00 0.201±0.16 0.981±0.14 0.027±0.03 0.017±0.00 0.044±0.00 0.030±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088N CIL_00088N_0002 VISTA 2:19155026-19755689
CIL_0002D0 CIL_0002D0_0002 CGP 2:19371440-19447501
CIL_000782 CIL_000782_0003 CGP 2:19445663-19553914

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 ISS DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 ISS transcription factor complex
GO:0005737 ISS cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0009790 IDA embryo development
GO:0009888 ISS tissue development
GO:0010842 IMP retina layer formation
GO:0021549 IMP cerebellum development
GO:0030154 IMP cell differentiation
GO:0030902 IDA hindbrain development
GO:0031016 IMP pancreas development
GO:0031017 ISS exocrine pancreas development
GO:0031018 TAS endocrine pancreas development
GO:0035881 IMP amacrine cell differentiation
GO:0043565 IDA sequence-specific DNA binding
GO:0045165 IMP cell fate commitment
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:0048384 IDA retinoic acid receptor signaling pathway
GO:0048663 IDA neuron fate commitment
GO:0048699 IDA generation of neurons
GO:0060042 IMP retina morphogenesis in camera-type eye
GO:0061074 IMP regulation of neural retina development
GO:0070888 IDA E-box binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000376504 PTF1A-001 protein_coding Homo_sapiens 0 1166

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