C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000028278 Psmd14-001 ENSMUSG00000026914 10090 + 2:61711694-61800376 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028278
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028278 18.099±0.41 4.761±0.83 21.559±2.19 36.905±3.81 13.376±4.32 6.436±1.78 12.820±0.27 12.756±1.61 26.907±18.50 11.234±2.05 24.028±0.92 14.790±12.79 38.263±8.68 9.728±1.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008JH CIL_0008JH_0002 VISTA 2:61356142-61956716
CIL_0005L0 CIL_0005L0_0002 CGP 2:61578585-61800376
CIL_0007OV CIL_0007OV_0002 UCNEbase 2:61656329-61774192
CIL_0005L1 CIL_0005L1_0002 CGP 2:61711694-61814114

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000502 IDA proteasome complex
GO:0000724 ISS double-strand break repair via homologous recombination
GO:0004175 ISS endopeptidase activity
GO:0004221 ISS ubiquitin thiolesterase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006303 ISS double-strand break repair via nonhomologous end joining
GO:0006508 IEA proteolysis
GO:0008237 IEA metallopeptidase activity
GO:0008541 ISS proteasome regulatory particle, lid subcomplex
GO:0010950 IEA positive regulation of endopeptidase activity
GO:0022624 IDA proteasome accessory complex
GO:0046872 IEA metal ion binding
GO:0061133 IEA endopeptidase activator activity
GO:0061136 IEA regulation of proteasomal protein catabolic process
GO:0070062 IEA extracellular vesicular exosome
GO:0070536 ISS protein K63-linked deubiquitination
GO:0070628 IEA proteasome binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000409682 PSMD14-001 protein_coding Homo_sapiens 0 1724
ENST00000437630 PSMD14-002 protein_coding Homo_sapiens 0 472
ENST00000477232 PSMD14-005 retained_intron Homo_sapiens 0 909
ENST00000478123 PSMD14-003 retained_intron Homo_sapiens 1.4013e-45 187
ENST00000492908 PSMD14-006 retained_intron Homo_sapiens 0 422

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