C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000409682 PSMD14-001 ENSG00000115233 9606 + 2:161308038-161411717 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000409682
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000409682 9.286±0.00 9.936±0.00 2.209±0.00 11.821±4.60 5.971±2.79 10.363±4.67 10.049±4.50 5.547±0.45 13.974±6.99 3.742±0.83 7.526±3.02 14.509±3.88 41.186±32.04 34.018±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008JH CIL_0008JH_0001 VISTA 2:160938384-161538940
CIL_0005L0 CIL_0005L0_0001 CGP 2:161136908-161411717
CIL_0007OV CIL_0007OV_0001 UCNEbase 2:161238541-161382542
CIL_0005L1 CIL_0005L1_0001 CGP 2:161308038-161425870

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0000724 IMP double-strand break repair via homologous recombination
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004221 TAS ubiquitin thiolesterase activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006303 IMP double-strand break repair via nonhomologous end joining
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008237 TAS metallopeptidase activity
GO:0008541 IMP proteasome regulatory particle, lid subcomplex
GO:0010467 TAS gene expression
GO:0010950 IMP positive regulation of endopeptidase activity
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0022624 ISS proteasome accessory complex
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0061133 IMP endopeptidase activator activity
GO:0061136 IMP regulation of proteasomal protein catabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0070536 TAS protein K63-linked deubiquitination
GO:0070628 IDA proteasome binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028278 Psmd14-001 protein_coding Mus_musculus 0 1724
ENSMUST00000121149 Gm12096-001 processed_pseudogene Mus_musculus 0 976
ENSMUST00000125388 Psmd14-008 processed_transcript Mus_musculus 0 730
ENSMUST00000154627 Psmd14-007 processed_transcript Mus_musculus 0 701
ENSMUST00000146051 Psmd14-004 processed_transcript Mus_musculus 0 466
ENSMUST00000153683 Psmd14-003 processed_transcript Mus_musculus 0 455
ENSMUST00000139475 Psmd14-002 processed_transcript Mus_musculus 2.8026e-45 187
ENSMUST00000134658 Psmd14-006 processed_transcript Mus_musculus 9.80909e-45 185
ENSMUST00000135265 Psmd14-005 processed_transcript Mus_musculus 0.000000000000003 88

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