C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: frizzled-related protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000028389 Frzb-001 ENSMUSG00000027004 10090 - 2:80411970-80447625 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028389
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028389 2.895±2.34 218.174±51.15 2.443±0.05 1.708±0.68 0.886±0.68 3.398±0.96 1.478±0.13 3.904±0.57 0.438±0.12 0.213±0.08 1.174±0.33 3.428±1.44 0.540±0.67 1.694±0.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YV CIL_0000YV_0002 CGP 2:80315466-80447625
CIL_0000YU CIL_0000YU_0002 CGP 2:80411970-80581380

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001944 IBA vasculature development
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0005615 IBA extracellular space
GO:0005737 IBA cytoplasm
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0007420 IBA brain development
GO:0008285 IEA negative regulation of cell proliferation
GO:0008406 IBA gonad development
GO:0010721 IDA negative regulation of cell development
GO:0014033 IEP neural crest cell differentiation
GO:0016055 IEA Wnt signaling pathway
GO:0017147 IPI Wnt-protein binding
GO:0030165 IBA PDZ domain binding
GO:0030178 IGI negative regulation of Wnt signaling pathway
GO:0030308 IEA negative regulation of cell growth
GO:0042472 IDA inner ear morphogenesis
GO:0042813 IBA Wnt-activated receptor activity
GO:0043065 IEA positive regulation of apoptotic process
GO:0045600 ISO positive regulation of fat cell differentiation
GO:0060029 IGI convergent extension involved in organogenesis
GO:0060056 IBA mammary gland involution
GO:0061037 IGI negative regulation of cartilage development
GO:0061053 IEP somite development
GO:0070367 IDA negative regulation of hepatocyte differentiation
GO:0090090 IGI negative regulation of canonical Wnt signaling pathway
GO:0090103 IGI cochlea morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000122177 frzb-201 protein_coding Danio_rerio 0 335
ENSDART00000002633 frzb-001 protein_coding Danio_rerio 0 335
ENST00000295113 FRZB-001 protein_coding Homo_sapiens 0 1362

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