C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mesoderm posterior 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000032760 Mesp1-001 ENSMUSG00000030544 10090 - 7:79792241-79793788 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENSMUST00000032760
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENSMUST00000032760 0.092±0.06 0.111±0.06 0.033±0.02 0.029±0.02 0.087±0.04 0.087±0.03 0.023±0.00 0.033±0.01 0.030±0.02 7.798±1.22 0.071±0.00 0.195±0.08 47.578±12.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00052Y CIL_00052Y_0002 CGP 7:79743163-79793788
CIL_0002RA CIL_0002RA_0004 CGP 7:79792241-79813431

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001947 IMP heart looping
GO:0003007 IMP heart morphogenesis
GO:0003139 IDA secondary heart field specification
GO:0003143 IMP embryonic heart tube morphogenesis
GO:0003210 IEA cardiac atrium formation
GO:0003211 IEA cardiac ventricle formation
GO:0003236 IMP sinus venosus morphogenesis
GO:0003241 IMP growth involved in heart morphogenesis
GO:0003259 IEP cardioblast anterior-lateral migration
GO:0003260 IMP cardioblast migration
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007219 IEA Notch signaling pathway
GO:0007369 IEP gastrulation
GO:0008078 IGI mesodermal cell migration
GO:0022008 IEA neurogenesis
GO:0023019 IDA signal transduction involved in regulation of gene expression
GO:0035326 IDA enhancer binding
GO:0035481 IDA positive regulation of Notch signaling pathway involved in heart induction
GO:0042662 IDA negative regulation of mesodermal cell fate specification
GO:0042664 IDA negative regulation of endodermal cell fate specification
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045446 IEA endothelial cell differentiation
GO:0045747 IDA positive regulation of Notch signaling pathway
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:0048368 IEP lateral mesoderm development
GO:0051155 IDA positive regulation of striated muscle cell differentiation
GO:0055007 IEA cardiac muscle cell differentiation
GO:0060913 IDA cardiac cell fate determination
GO:0060921 IEA sinoatrial node cell differentiation
GO:0060947 IEA cardiac vascular smooth muscle cell differentiation
GO:0060975 IMP cardioblast migration to the midline involved in heart field formation
GO:0070368 IDA positive regulation of hepatocyte differentiation
GO:0090082 IDA positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000300057 MESP1-001 protein_coding Homo_sapiens 0 261
ENST00000341735 MESP2-001 protein_coding Homo_sapiens 0 259

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