C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033131 Lamtor1-201 ENSMUSG00000030842 10090 + 7:101905837-101911901 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033131
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033131 121.475±33.80 92.820±10.83 58.194±7.94 65.411±34.22 94.251±21.96 88.978±2.95 77.039±6.27 87.854±5.81 59.913±10.18 67.224±2.68 53.985±8.19 74.502±19.41 86.442±31.52 17.538±4.95

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XL CIL_0008XL_0002 VISTA 7:101413526-102014552
CIL_0002MI CIL_0002MI_0002 CGP 7:101898373-101911901
CIL_000303 CIL_000303_0002 CGP 7:101905837-101933895

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001919 IMP regulation of receptor recycling
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005764 ISS lysosome
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0007032 IMP endosome organization
GO:0007040 IMP lysosome organization
GO:0010872 ISS regulation of cholesterol esterification
GO:0010874 ISS regulation of cholesterol efflux
GO:0016049 ISS cell growth
GO:0031902 ISS late endosome membrane
GO:0032008 ISS positive regulation of TOR signaling
GO:0032418 IMP lysosome localization
GO:0032439 IMP endosome localization
GO:0032947 ISS protein complex scaffold
GO:0034613 IMP cellular protein localization
GO:0042632 ISS cholesterol homeostasis
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043410 IMP positive regulation of MAPK cascade
GO:0043547 ISS positive regulation of GTPase activity
GO:0045121 ISS membrane raft
GO:0060620 ISS regulation of cholesterol import
GO:0070062 IEA extracellular vesicular exosome
GO:0071230 ISS cellular response to amino acid stimulus
GO:0071986 ISS Ragulator complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000278671 LAMTOR1-001 protein_coding Homo_sapiens 0 1221
ENST00000535872 LAMTOR1-002 nonsense_mediated_decay Homo_sapiens 0 861
ENST00000538404 LAMTOR1-004 protein_coding Homo_sapiens 0 579
ENST00000539797 LAMTOR1-007 processed_transcript Homo_sapiens 0 640
ENST00000544594 LAMTOR1-003 protein_coding Homo_sapiens 0 531
ENST00000545249 LAMTOR1-006 protein_coding Homo_sapiens 0 597

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