C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polo-like kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033154 Plk1-201 ENSMUSG00000030867 10090 + 7:122159437-122169875 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033154
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033154 2.762±1.90 0.613±0.31 1.283±0.09 8.847±5.98 1.016±0.55 15.620±2.79 0.290±0.04 0.290±0.18 21.726±26.02 1.096±0.16 0.106±0.05 8.302±3.02 18.641±13.24 22.551±5.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006D0 CIL_0006D0_0002 CGP 7:122133041-122169875
CIL_0003VD CIL_0003VD_0003 CGP 7:122159437-122186216

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000070 ISS mitotic sister chromatid segregation
GO:0000086 ISS G2/M transition of mitotic cell cycle
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000281 ISS mitotic cytokinesis
GO:0000776 ISS kinetochore
GO:0000910 IEA cytokinesis
GO:0000922 ISO spindle pole
GO:0000942 IEA condensed nuclear chromosome outer kinetochore
GO:0001578 ISS microtubule bundle formation
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0005813 ISS centrosome
GO:0005819 ISS spindle
GO:0005876 IEA spindle microtubule
GO:0006468 ISS protein phosphorylation
GO:0007067 ISS mitotic nuclear division
GO:0007092 ISS activation of mitotic anaphase-promoting complex activity
GO:0007094 ISS mitotic spindle assembly checkpoint
GO:0007346 IEA regulation of mitotic cell cycle
GO:0008017 ISS microtubule binding
GO:0010800 IEA positive regulation of peptidyl-threonine phosphorylation
GO:0010997 IEA anaphase-promoting complex binding
GO:0015630 IEA microtubule cytoskeleton
GO:0016567 IEA protein ubiquitination
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0030071 IEA regulation of mitotic metaphase/anaphase transition
GO:0030496 ISS midbody
GO:0031572 ISS G2 DNA damage checkpoint
GO:0031648 IEA protein destabilization
GO:0032436 ISS positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0040038 IEA polar body extrusion after meiotic divisions
GO:0043066 ISS negative regulation of apoptotic process
GO:0043393 IEA regulation of protein binding
GO:0045184 ISO establishment of protein localization
GO:0045736 IEA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045862 IEA positive regulation of proteolysis
GO:0046677 IEA response to antibiotic
GO:0051233 ISS spindle midzone
GO:0051297 ISS centrosome organization
GO:0051443 ISS positive regulation of ubiquitin-protein transferase activity
GO:0071168 ISS protein localization to chromatin

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000300093 PLK1-001 protein_coding Homo_sapiens 0 2331
ENST00000518921 CTD-2571E19.3-001 processed_pseudogene Homo_sapiens 0 773
ENST00000562272 PLK1-002 retained_intron Homo_sapiens 0 1881
ENST00000564202 PLK1-006 processed_transcript Homo_sapiens 0 545
ENST00000564794 PLK1-010 retained_intron Homo_sapiens 0 573
ENST00000564947 PLK1-005 retained_intron Homo_sapiens 0 281
ENST00000567897 PLK1-007 protein_coding Homo_sapiens 0 808
ENST00000568568 PLK1-008 protein_coding Homo_sapiens 0 634
ENST00000570220 PLK1-004 nonsense_mediated_decay Homo_sapiens 0 394

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