C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: CD40 ligand
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033466 Cd40lg-001 ENSMUSG00000031132 10090 + X:57212143-57224042 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033466
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033466 0.086±0.05 0.109±0.00 0.056±0.00 1.929±0.46 0.216±0.09 0.076±0.02 0.130±0.08 0.075±0.05 0.252±0.04 0.100±0.00 0.076±0.06 0.022±0.00 0.107±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000JS CIL_0000JS_0002 CGP X:57088106-57224042
CIL_0000JT CIL_0000JT_0002 CGP X:57212143-57338729

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005125 IEA cytokine activity
GO:0005164 IEA tumor necrosis factor receptor binding
GO:0005174 ISS CD40 receptor binding
GO:0005615 IEA extracellular space
GO:0006954 ISS inflammatory response
GO:0007165 NAS signal transduction
GO:0009897 IDA external side of plasma membrane
GO:0016021 IEA integral component of membrane
GO:0030168 ISS platelet activation
GO:0030183 IGI B cell differentiation
GO:0032735 IEA positive regulation of interleukin-12 production
GO:0042100 ISS B cell proliferation
GO:0043066 ISS negative regulation of apoptotic process
GO:0045190 IDA isotype switching
GO:0048305 IGI immunoglobulin secretion
GO:0051023 IDA regulation of immunoglobulin secretion
GO:2000353 IEA positive regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000370628 CD40LG-002 protein_coding Homo_sapiens 0 551
ENST00000370629 CD40LG-001 protein_coding Homo_sapiens 0 961

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