C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Werner syndrome homolog (human)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033991 Wrn-202 ENSMUSG00000031583 10090 - 8:33234384-33385527 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033991
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033991 0.371±0.05 0.871±0.20 1.573±0.34 1.012±0.52 0.959±0.35 0.735±0.65 0.684±0.24 1.234±0.76 0.345±0.11 0.247±0.12 1.339±0.75 1.718±0.80 1.313±0.43

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KM CIL_0006KM_0002 CGP 8:31818028-33385527
CIL_0006KJ CIL_0006KJ_0002 CGP 8:33234384-33417468

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0000723 IMP telomere maintenance
GO:0001302 IMP replicative cell aging
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 ISO nucleolus
GO:0006200 IEA ATP catabolic process
GO:0006259 ISS DNA metabolic process
GO:0006260 IMP DNA replication
GO:0006302 ISS double-strand break repair
GO:0006310 IEA DNA recombination
GO:0008408 ISS 3'-5' exonuclease activity
GO:0009267 ISO cellular response to starvation
GO:0010259 IGI multicellular organismal aging
GO:0030145 ISS manganese ion binding
GO:0032066 ISO nucleolus to nucleoplasm transport
GO:0032508 IEA DNA duplex unwinding
GO:0040009 IMP regulation of growth rate
GO:0043140 IEA ATP-dependent 3'-5' DNA helicase activity
GO:0071480 ISS cellular response to gamma radiation
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000298139 WRN-001 protein_coding Homo_sapiens 0 2122
ENST00000520169 WRN-003 retained_intron Homo_sapiens 0 335
ENST00000521620 WRN-002 retained_intron Homo_sapiens 0 1857

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