C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: chemokine (C-X3-C motif) ligand 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000034230 Cx3cl1-001 ENSMUSG00000031778 10090 + 8:94772009-94782423 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034230
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034230 4.305±1.14 33.599±2.51 10.458±0.67 32.420±34.86 12.753±3.88 37.370±4.26 3.191±0.77 44.502±3.90 0.293±0.14 25.412±6.20 0.541±0.10 11.118±3.48 2.636±2.20 1.390±0.66

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003ZH CIL_0003ZH_0002 CGP 8:94745590-94782423
CIL_0003ZE CIL_0003ZE_0002 CGP 8:94772009-94812035

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0006935 ISS chemotaxis
GO:0006955 IEA immune response
GO:0007155 IEA cell adhesion
GO:0008009 IDA chemokine activity
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0019221 IMP cytokine-mediated signaling pathway
GO:0030593 IDA neutrophil chemotaxis
GO:0032914 IMP positive regulation of transforming growth factor beta1 production
GO:0042060 IMP wound healing
GO:0045766 IMP positive regulation of angiogenesis
GO:0048246 IMP macrophage chemotaxis
GO:0048247 IDA lymphocyte chemotaxis
GO:0050729 IEA positive regulation of inflammatory response
GO:0051041 IEA positive regulation of calcium-independent cell-cell adhesion
GO:0060055 IMP angiogenesis involved in wound healing
GO:2001240 IDA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000006053 CX3CL1-001 protein_coding Homo_sapiens 3e-18 99
ENST00000563383 CX3CL1-002 protein_coding Homo_sapiens 5e-16 92
ENST00000565912 CX3CL1-003 protein_coding Homo_sapiens 2e-16 94

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