C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: iron responsive element binding protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000034843 Ireb2-201 ENSMUSG00000032293 10090 + 9:54863755-54912534 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034843
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034843 5.507±2.82 2.709±0.68 6.224±0.88 16.052±8.08 4.162±1.37 2.987±1.13 3.347±0.24 6.796±1.01 8.153±1.49 6.079±0.69 4.287±0.51 6.450±3.73 14.841±2.47 10.972±3.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00020I CIL_00020I_0002 CGP 9:54764748-54912534
CIL_0001UQ CIL_0001UQ_0002 CGP 9:54863755-54949924

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003723 IEA RNA binding
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 IDA cytosol
GO:0006417 IMP regulation of translation
GO:0006782 IMP protoporphyrinogen IX biosynthetic process
GO:0006826 IEA iron ion transport
GO:0006879 IDA cellular iron ion homeostasis
GO:0007568 IEA aging
GO:0009791 IGI post-embryonic development
GO:0010040 IEA response to iron(II) ion
GO:0010468 IGI regulation of gene expression
GO:0017148 IEA negative regulation of translation
GO:0030316 IEP osteoclast differentiation
GO:0030350 IDA iron-responsive element binding
GO:0030371 TAS translation repressor activity
GO:0032526 IEA response to retinoic acid
GO:0034101 IMP erythrocyte homeostasis
GO:0046872 IEA metal ion binding
GO:0050892 IGI intestinal absorption
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0055072 IGI iron ion homeostasis
GO:0071456 IEA cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000258886 IREB2-001 protein_coding Homo_sapiens 0 4566
ENST00000558525 IREB2-008 nonsense_mediated_decay Homo_sapiens 0 1242
ENST00000558570 IREB2-003 nonsense_mediated_decay Homo_sapiens 0 2950
ENST00000559091 IREB2-009 protein_coding Homo_sapiens 0 311
ENST00000559215 IREB2-006 nonsense_mediated_decay Homo_sapiens 0 460
ENST00000559427 IREB2-007 processed_transcript Homo_sapiens 0 568
ENST00000559676 IREB2-010 retained_intron Homo_sapiens 0 767
ENST00000560440 IREB2-002 protein_coding Homo_sapiens 0 1548
ENST00000560454 IREB2-005 processed_transcript Homo_sapiens 3e-35 152
ENST00000560840 IREB2-004 protein_coding Homo_sapiens 0 398

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