C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adrenergic receptor, alpha 2a
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000036700 Adra2a-201 ENSMUSG00000033717 10090 + 19:54045182-54048982 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000036700
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000036700 1.193±0.20 0.202±0.09 0.136±0.04 3.769±1.13 2.944±1.36 15.703±2.28 0.054±0.03 0.777±0.09 0.125±0.11 0.646±0.05 0.143±0.10 2.596±0.93 0.368±0.20 0.176±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006FA CIL_0006FA_0002 CGP 19:53944306-54048982
CIL_0006FB CIL_0006FB_0002 CGP 19:54045182-55099451

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001819 IEA positive regulation of cytokine production
GO:0002526 IEA acute inflammatory response
GO:0004935 IMP adrenergic receptor activity
GO:0004938 TAS alpha2-adrenergic receptor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006260 IEA DNA replication
GO:0007165 IEA signal transduction
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0007565 IEA female pregnancy
GO:0019229 IEA regulation of vasoconstriction
GO:0019901 IEA protein kinase binding
GO:0030168 IEA platelet activation
GO:0030335 IEA positive regulation of cell migration
GO:0031696 IEA alpha-2C adrenergic receptor binding
GO:0031996 IEA thioesterase binding
GO:0032147 IEA activation of protein kinase activity
GO:0032148 IEA activation of protein kinase B activity
GO:0032795 IEA heterotrimeric G-protein binding
GO:0032870 IEA cellular response to hormone stimulus
GO:0035625 IEA epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
GO:0042593 IEA glucose homeostasis
GO:0042596 IMP fear response
GO:0042803 IEA protein homodimerization activity
GO:0043235 IEA receptor complex
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0045202 IEA synapse
GO:0045741 IEA positive regulation of epidermal growth factor-activated receptor activity
GO:0045909 IEA positive regulation of vasodilation
GO:0045955 IEA negative regulation of calcium ion-dependent exocytosis
GO:0046676 IEA negative regulation of insulin secretion
GO:0050955 IEA thermoception
GO:0050995 IEA negative regulation of lipid catabolic process
GO:0051044 IEA positive regulation of membrane protein ectodomain proteolysis
GO:0051379 IEA epinephrine binding
GO:0051380 IEA norepinephrine binding
GO:0061179 IEA negative regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070473 IEA negative regulation of uterine smooth muscle contraction
GO:0071881 IEA adenylate cyclase-inhibiting adrenergic receptor signaling pathway
GO:0071882 IEA phospholipase C-activating adrenergic receptor signaling pathway
GO:0071883 IEA activation of MAPK activity by adrenergic receptor signaling pathway
GO:0090303 IEA positive regulation of wound healing

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000059869 adra2a-001 protein_coding Danio_rerio 3.99931e-42 178
ENST00000280155 ADRA2A-001 protein_coding Homo_sapiens 0 2041
ENST00000620793 ADRA2B-001 protein_coding Homo_sapiens 1e-37 163

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