C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ring finger and WD repeat domain 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000038739 Rfwd3-201 ENSMUSG00000033596 10090 - 8:111270944-111300222 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038739
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038739 6.916±2.74 11.873±2.07 5.304±1.11 5.967±2.62 6.287±0.98 7.510±0.97 4.442±0.11 5.776±0.47 10.317±7.72 6.157±0.31 1.092±0.22 18.807±3.67 15.976±6.32 10.308±3.68

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002I2 CIL_0002I2_0002 CGP 8:111154421-111300222
CIL_0002PQ CIL_0002PQ_0002 CGP 8:111270944-111338177

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002039 ISS p53 binding
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0006281 IEA DNA repair
GO:0008270 IEA zinc ion binding
GO:0010212 ISS response to ionizing radiation
GO:0016567 ISS protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031571 ISS mitotic G1 DNA damage checkpoint
GO:0035861 IEA site of double-strand break
GO:0097371 ISS MDM2/MDM4 family protein binding
GO:2000001 IEA regulation of DNA damage checkpoint

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000361070 RFWD3-001 protein_coding Homo_sapiens 0 1304
ENST00000571750 RFWD3-002 protein_coding Homo_sapiens 0 1304
ENST00000572610 RFWD3-004 retained_intron Homo_sapiens 0 239
ENST00000575154 RFWD3-005 retained_intron Homo_sapiens 0 459
ENST00000575281 RFWD3-006 retained_intron Homo_sapiens 0 383

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