C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000039259 Agap2-201 ENSMUSG00000025422 10090 + 10:127078907-127093169 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000039259
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000039259 4.486±3.89 2.660±0.39 1.578±0.15 101.955±25.13 5.741±4.13 1.823±0.18 0.841±0.11 0.339±0.10 0.318±0.23 0.942±0.19 0.823±0.08 5.164±2.04 0.079±0.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0005739 IEA mitochondrion
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0019901 IEA protein kinase binding
GO:0030295 IEA protein kinase activator activity
GO:0032312 IEA regulation of ARF GTPase activity
GO:0033601 IGI positive regulation of mammary gland epithelial cell proliferation
GO:0043066 IMP negative regulation of apoptotic process
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0045860 IEA positive regulation of protein kinase activity
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046427 IMP positive regulation of JAK-STAT cascade
GO:0060749 IMP mammary gland alveolus development
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000257897 AGAP2-001 protein_coding Homo_sapiens 0 2427
ENST00000328568 AGAP2-003 protein_coding Homo_sapiens 0 2651
ENST00000547588 AGAP2-002 protein_coding Homo_sapiens 0 4588
ENST00000549129 AGAP2-005 protein_coding Homo_sapiens 0 640
ENST00000553221 TSPAN31-013 processed_transcript Homo_sapiens 0 268

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