C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: topoisomerase I binding, arginine/serine-rich
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000042575 Topors-001 ENSMUSG00000036822 10090 - 4:40259601-40269850 protein_coding

Mus musculus EnsemblGRCm38

Genome
Exciting message
Genes
Structures from Ensembl
Connecting
Transcripts
Structures from Ensembl
Connecting
Powered by Dalliance 0.11.11

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042575
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042575 3.690±1.08 6.741±0.64 7.035±0.56 6.231±0.29 3.765±0.89 3.569±0.39 3.495±0.25 4.905±2.12 4.699±0.11 2.612±0.15 7.506±5.01 15.294±5.97 15.154±22.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00065D CIL_00065D_0002 CGP 4:40203773-40269850
CIL_00061N CIL_00061N_0002 CGP 4:40259601-40279421

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000151 IEA ubiquitin ligase complex
GO:0000922 IEA spindle pole
GO:0000930 IEA gamma-tubulin complex
GO:0003677 IEA DNA binding
GO:0003823 IEA antigen binding
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005814 IEA centriole
GO:0006511 ISS ubiquitin-dependent protein catabolic process
GO:0006513 IEA protein monoubiquitination
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0008270 IEA zinc ion binding
GO:0008630 ISS intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016605 ISS PML body
GO:0016607 ISS nuclear speck
GO:0016925 ISS protein sumoylation
GO:0019789 ISS SUMO ligase activity
GO:0032391 IDA photoreceptor connecting cilium
GO:0034504 ISS protein localization to nucleus
GO:0036064 IDA ciliary basal body
GO:0042127 IDA regulation of cell proliferation
GO:0042771 IDA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044547 IEA DNA topoisomerase binding
GO:0045893 IGI positive regulation of transcription, DNA-templated
GO:0051443 IEA positive regulation of ubiquitin-protein transferase activity
GO:0051457 IEA maintenance of protein location in nucleus
GO:0070936 IEA protein K48-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000058174 toporsb-201 protein_coding Danio_rerio 0.00007 55
ENST00000360538 TOPORS-001 protein_coding Homo_sapiens 0 3524
ENST00000379858 TOPORS-002 protein_coding Homo_sapiens 0 3306

Loading