C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine (or cysteine) peptidase inhibitor, clade F, member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000043696 Serpinf2-201 ENSMUSG00000038224 10090 - 11:75431736-75439501 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043696
Transcript ID Adipose Adrenal Bladder Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043696 0.123±0.05 0.249±0.20 0.018±0.01 1.515±0.23 0.650±0.27 35.557±3.10 442.986±108.61 0.379±0.00 0.016±0.00 0.470±0.38 24.329±29.97 0.159±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039V CIL_00039V_0002 CGP 11:75431732-75454717

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0002034 IMP regulation of blood vessel size by renin-angiotensin
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005577 IEA fibrinogen complex
GO:0005615 IBA extracellular space
GO:0006953 IEA acute-phase response
GO:0009986 IEA cell surface
GO:0010033 IEA response to organic substance
GO:0010757 IEA negative regulation of plasminogen activation
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0030199 IMP collagen fibril organization
GO:0032967 IMP positive regulation of collagen biosynthetic process
GO:0042803 IEA protein homodimerization activity
GO:0045597 IMP positive regulation of cell differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046330 IEA positive regulation of JNK cascade
GO:0048514 IMP blood vessel morphogenesis
GO:0048661 IMP positive regulation of smooth muscle cell proliferation
GO:0051496 IEA positive regulation of stress fiber assembly
GO:0051918 IEA negative regulation of fibrinolysis
GO:0070062 IEA extracellular vesicular exosome
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0071636 IMP positive regulation of transforming growth factor beta production
GO:0072562 IEA blood microparticle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000324015 SERPINF2-201 protein_coding Homo_sapiens 0 1295
ENST00000382061 SERPINF2-001 protein_coding Homo_sapiens 0 1288
ENST00000450523 SERPINF2-004 protein_coding Homo_sapiens 0 1035
ENST00000453066 SERPINF2-002 protein_coding Homo_sapiens 0 656
ENST00000453723 SERPINF2-003 protein_coding Homo_sapiens 0 425
ENST00000615103 SERPINF2-202 protein_coding Homo_sapiens 0 1035
ENST00000618883 SERPINF2-203 protein_coding Homo_sapiens 0 1290
ENST00000622842 SERPINF2-204 protein_coding Homo_sapiens 0 1282

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