C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: prostaglandin E receptor 4 (subtype EP4)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000302472 PTGER4-001 ENSG00000171522 9606 + 5:40679498-40693735 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302472
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302472 4.421±0.00 0.220±0.20 7.287±0.57 3.514±2.70 1.135±0.75 7.134±0.00 0.826±0.42 2.797±0.00 1.125±0.19 0.576±0.26 0.842±0.40 1.601±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006MD CIL_0006MD_0002 CGP 5:40679498-40755975

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004957 IDA prostaglandin E receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0006955 IEP immune response
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007188 IDA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007254 ISS JNK cascade
GO:0009612 IEP response to mechanical stimulus
GO:0016021 NAS:IEA integral component of membrane
GO:0030278 IEA regulation of ossification
GO:0032496 IEA response to lipopolysaccharide
GO:0033624 IDA negative regulation of integrin activation
GO:0042093 ISS T-helper cell differentiation
GO:0050710 ISS negative regulation of cytokine secretion
GO:0050715 ISS positive regulation of cytokine secretion
GO:0050728 IDA negative regulation of inflammatory response
GO:0050729 ISS positive regulation of inflammatory response
GO:0051492 ISS regulation of stress fiber assembly
GO:0060348 ISS bone development
GO:0070371 ISS ERK1 and ERK2 cascade
GO:0071260 ISS cellular response to mechanical stimulus
GO:2000420 IDA negative regulation of eosinophil extravasation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000120563 Ptger4-002 protein_coding Mus_musculus 0 1703
ENSMUST00000047379 Ptger4-001 protein_coding Mus_musculus 0 1567
ENSMUST00000133966 Ptger4-003 processed_transcript Mus_musculus 0 523

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