C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000047421 Tie1-001 ENSMUSG00000033191 10090 - 4:118471191-118490061 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047421
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047421 30.364±11.54 20.842±5.36 9.091±0.79 5.852±1.84 16.895±4.30 8.290±1.32 19.392±1.19 17.749±2.05 4.663±1.56 84.049±26.89 6.224±0.62 18.723±5.88 8.387±3.43 0.567±0.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003N3 CIL_0003N3_0002 CGP 4:118442415-118490061

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001568 IMP blood vessel development
GO:0001570 IEA vasculogenesis
GO:0001701 IGI in utero embryonic development
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005886 IDA plasma membrane
GO:0016021 ISM integral component of membrane
GO:0016525 IMP negative regulation of angiogenesis
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030336 IMP negative regulation of cell migration
GO:0032526 IDA response to retinoic acid
GO:0045026 IMP plasma membrane fusion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000372476 TIE1-001 protein_coding Homo_sapiens 0 4030
ENST00000461061 TIE1-008 processed_transcript Homo_sapiens 0 462
ENST00000471187 TIE1-007 processed_transcript Homo_sapiens 0 472
ENST00000473014 TIE1-003 processed_transcript Homo_sapiens 0 529
ENST00000480269 TIE1-005 processed_transcript Homo_sapiens 0 324
ENST00000488437 TIE1-006 processed_transcript Homo_sapiens 0 592
ENST00000538015 TIE1-201 protein_coding Homo_sapiens 0 1133

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