C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000372476 TIE1-001 ENSG00000066056 9606 + 1:43300993-43323108 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000372476
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000372476 52.616±0.00 39.280±0.00 1.149±0.00 1.439±0.61 12.220±10.25 13.009±12.52 5.141±4.26 4.370±2.79 2.338±0.76 20.844±18.13 3.854±2.77 6.774±4.97 67.347±31.18 5.024±2.97

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008N2 CIL_0008N2_0001 VISTA 1:42758169-43359178

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001568 IEA blood vessel development
GO:0001570 IEA vasculogenesis
GO:0001701 IEA in utero embryonic development
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007498 TAS mesoderm development
GO:0016525 IEA negative regulation of angiogenesis
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030336 IEA negative regulation of cell migration
GO:0032526 IEA response to retinoic acid
GO:0045026 IEA plasma membrane fusion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000047421 Tie1-001 protein_coding Mus_musculus 0 4030
ENSMUST00000153286 Tie1-003 processed_transcript Mus_musculus 0 2662
ENSMUST00000184261 Tie1-002 protein_coding Mus_musculus 0 2108

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